COL3A1 anticorps (Chain alpha 1)

N° du produit ABIN272016

Détail du produit anti-COL3A1 anticorps

Antigène: COL3A1 (Collagen, Type III, alpha 1 (COL3A1))

Épitope: Chain alpha 1

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COL3A1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects endogenous levels of Collagen III protein (COL3A1).

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity Chromatography using epitope-specific immunogen

Information d'application

Indications d'application: ELISA: 1/10000approx. 1/20000. Immunoflourescence: 1/50approx. 1/200. Immunohistochemistry: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH ~7.2, 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Références pour anticorps anti-COL3A1 (ABIN272016)

Xie, Dolder, Siegrist, Wetterwald, Hofstetter: "Glutamate Receptor Agonists and Glutamate Transporter Antagonists Regulate Differentiation of Osteoblast Lineage Cells." dans: Calcified tissue international, Vol. 99, Issue 2, pp. 142-54, (2018) (PubMed).

Schminke, Frese, Bode, Goldring, Miosge: "Laminins and Nidogens in the Pericellular Matrix of Chondrocytes: Their Role in Osteoarthritis and Chondrogenic Differentiation." dans: The American journal of pathology, Vol. 186, Issue 2, pp. 410-8, (2016) (PubMed).

Chen, Yang, Huang, Pan, Liu, Qiu: "Angiotensin-(1-7) attenuates lung fibrosis by way of Mas receptor in acute lung injury." dans: The Journal of surgical research, Vol. 185, Issue 2, pp. 740-7, (2013) (PubMed).

Xie, Li, Wang, Zhang, Peng, Yang, Zou, Ge, Chen, Chen: "In vivo delivery of adenoviral vector containing interleukin-17 receptor a reduces cardiac remodeling and improves myocardial function in viral myocarditis leading to dilated cardiomyopathy." dans: PLoS ONE, Vol. 8, Issue 8, pp. e72158, (2013) (PubMed).

Zhang, Shen, Zhang, Wan, Yao, Wu, Wang, Chen, Yan, Jiang: "Induction of thoracic aortic remodeling by endothelial-specific deletion of microRNA-21 in mice." dans: PLoS ONE, Vol. 8, Issue 3, pp. e59002, (2013) (PubMed).

Détails sur COL3A1

Antigène: COL3A1 (Collagen, Type III, alpha 1 (COL3A1))

Abstract: COL3A1 Produits

Synonymes: anticorps EDS4A, anticorps AW550625, anticorps Col3a-1, anticorps MMS10-W, anticorps Ms10w, anticorps mKIAA4231, anticorps col3a1, anticorps collagen type III alpha 1 chain, anticorps collagen, type III, alpha 1, anticorps collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) S homeolog, anticorps COL3A1, anticorps Col3a1, anticorps col3a1, anticorps col3a1.S

Sujet: Collagen III is a fibrillar collagen that is found in extensible connective tissues such as skin, lung, and the vascular system, frequently in association with type I Collagen. Mutations in the gene are associated with Ehlers Danlos syndrome type IV, and with aortic and arterial aneurysms. Although alternate transcripts have been detected for this gene, they are the result of mutations, these mutations alter splicing, often leading to the exclusion of multiple exons.Synonyms: COL3A1

Poids moléculaire: approx. 138 kDa

ID gène: 1281

NCBI Accession: NP_000081

UniProt: P02461

Pathways: Autophagy, Growth Factor Binding