SMAD1 anticorps

N° du produit ABIN272123

Détail du produit anti-SMAD1 anticorps

Antigène: SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMAD1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of Smad1 protein. (region surrounding Pro183)

Réactivité croisée (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Pureté: > 95 % pure by SDS-PAGE

Information d'application

Indications d'application: ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: DO NOT FREEZE!

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur SMAD1

Antigène: SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))

Autre désignation: SMAD1 (SMAD1 Produits)

Synonymes: anticorps MLP, anticorps Xmad1, anticorps Xsmad1, anticorps bsp1, anticorps jv4-1, anticorps jv41, anticorps madh1, anticorps madr1, anticorps smad-1, anticorps MADH1, anticorps fb39h09, anticorps wu:fb39h09, anticorps wu:fb97e04, anticorps 2/23, anticorps CG12399, anticorps Dmel\\CG12399, anticorps E(zen)2, anticorps En(vvl), anticorps MAD, anticorps Mat, anticorps P-Mad, anticorps P-mad, anticorps PMad, anticorps Smad, anticorps Smad1, anticorps apg, anticorps c28, anticorps dMAD, anticorps dMad, anticorps l(2)K00237, anticorps l(2)k00237, anticorps mad, anticorps p-Mad, anticorps pMAD, anticorps pMad, anticorps pSmad, anticorps BSP-1, anticorps BSP1, anticorps JV4-1, anticorps JV41, anticorps MADR1, anticorps AI528653, anticorps Madh1, anticorps Madr1, anticorps Mlp1, anticorps MusMLP, anticorps smad1, anticorps xmad, anticorps SMAD family member 1, anticorps Mothers against dpp, anticorps SMAD family member 1 L homeolog, anticorps smad1, anticorps SMAD1, anticorps Mad, anticorps Smad1, anticorps smad1.L

Sujet: Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad) have been implicated as downstream effectors of TGFβ/BMP signaling. Smad1 (also designated Madr1 or JV4-1), Smad5 and mammalian Smad8 (also designated Smad9 or MadH6) are effectors of BMP2 and BMP4 function while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGFβ and activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFβ signaling by interfering with TGFβ-mediated phosphorylation of other Smad family members.Synonyms: BSP-1, BSP1, JV4-1, MAD homolog 1, MADH1, MADR1, Mad-related protein 1, Mothers against DPP homolog 1, Mothers against decapentaplegic homolog 1, SMAD 1, SMAD family member 1, SMAD-1, Transforming growth factor-beta-signaling protein 1

Poids moléculaire: approx. 60 kDa

ID gène: 4086

NCBI Accession: NP_001003688

UniProt: Q15797

Pathways: Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development