KLF11 anticorps

N° du produit ABIN272134

Détail du produit anti-KLF11 anticorps

Antigène: KLF11 (Kruppel-Like Factor 11 (KLF11))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KLF11 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of TIEG2 protein. (region surrounding Phe6)

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Pureté: > 95 % pure by SDS-PAGE

Information d'application

Indications d'application: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: DO NOT FREEZE!

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur KLF11

Antigène: KLF11 (Kruppel-Like Factor 11 (KLF11))

Autre désignation: KLF11 / TIEG2 (KLF11 Produits)

Synonymes: anticorps FKLF, anticorps FKLF1, anticorps MODY7, anticorps TIEG2, anticorps Tieg3, anticorps 9830142A17, anticorps D12Ertd427e, anticorps Tieg2, anticorps Tieg2b, anticorps Tcfcp2l2, anticorps KLF11, anticorps klf11, anticorps si:dkey-81b15.5, anticorps tieg3, anticorps wu:fc45c07, anticorps wu:fj44b12, anticorps zgc:153255, anticorps fklf, anticorps fklf1, anticorps mody7, anticorps tieg2, anticorps MGC145216, anticorps TIEG-2, anticorps zgc:154048, anticorps Kruppel like factor 11, anticorps Kruppel-like factor 11, anticorps Kruppel-like factor 11 L homeolog, anticorps Kruppel-like factor 11a, anticorps Krueppel-like factor 11, anticorps Kruppel-like factor 11b, anticorps KLF11, anticorps Klf11, anticorps klf11.L, anticorps klf11a, anticorps klf11, anticorps LOC100194692, anticorps klf11b

Sujet: Originally isolated from osteoblastic cells, the TGF-beta-inducible early gene-1 (TIEG1) is a Krupel-like zinc finger transcription factor-encoding gene which regulates cellular growth and differentiation. TIEG1 is regulated as an early response gene by TGFβ1. It is expressed in both acinar and ductular epithelial cells from exocrine pancreas and may serve as an early response gene in pancreatic cell lines. Further, overexpression of TIEG1 in TGFβ-sensitive epithelial cells induces apoptosis. TIEG1 and EGR-α are expressedfrom alternate promoters of the same gene. TIEG1 and EGR-α are both highly expressed in human fetal osteoblast cells. TIEG1 is additionally expressed at high levels in PBLs, spleen and colon, and at lower levels in thymus, small intestine, ovary, prostate and skeletal muscle. The nuclear TIEG2 protein, which shares significant homology with TIEG1, was originally isolated from globin-expressing human fetal eryth-roid cells. TIEG2 is also expressed in fetal liver. Overexpression of TIEG2 in cultured epithelial cells inhibits cellular proliferation, TIEG2 expression is upregulated by TGFβ1 and serum deprivation.Synonyms: FKLF, Krueppel-like factor 11, TGFB-inducible early growth response protein 2, TIEG-2, Transforming growth factor-beta-inducible early growth response protein 2

Poids moléculaire: approx. 55 kDa

ID gène: 8462

NCBI Accession: NP_001171187

UniProt: O14901