GAS41 anticorps

N° du produit ABIN272151

Détail du produit anti-GAS41 anticorps

Antigène: GAS41 (YEATS Domain Containing 4)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GAS41 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody detects endogenous levels of GAS41 protein. (region surrounding Arg32)

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Pureté: > 95 % pure by SDS-PAGE

Information d'application

Indications d'application: ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: DO NOT FREEZE!

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur GAS41

Antigène: GAS41 (YEATS Domain Containing 4)

Autre désignation: YEATS4 (GAS41 Produits)

Synonymes: anticorps 4930573H17Rik, anticorps B230215M10Rik, anticorps GAS41, anticorps NUBI-1, anticorps YAF9, anticorps YEATS4, anticorps NuBI-1, anticorps RGD1305741, anticorps zgc:100841, anticorps MGC89432, anticorps CG9207, anticorps Dmel\\CG9207, anticorps dGas41, anticorps GB13136, anticorps GLIOMAS 41, anticorps K2N11.8, anticorps K2N11_8, anticorps TAF14B, anticorps TBP-ASSOCIATED FACTOR 14B, anticorps NV13456, anticorps YEATS domain containing 4, anticorps YEATS domain containing 4 S homeolog, anticorps CG9207 gene product from transcript CG9207-RA, anticorps YEATS domain-containing protein 4, anticorps YEATS family protein, anticorps Gas41, anticorps gas41 homologue, putative, anticorps putative gas41, anticorps YEATS4, anticorps Yeats4, anticorps yeats4.S, anticorps yeats4, anticorps Gas41, anticorps LOC412705, anticorps GAS41, anticorps Chro.20029, anticorps PB300718.00.0, anticorps PCHAS_122420, anticorps Smp_070760, anticorps LOC100121822

Sujet: Gene amplification is associated with tumor stage and progression in human gliomas. Several amplified loci are identified and comprise multiple genes. The glioma amplified sequence 41 (GAS41) is an evolutionarily conserved eukaryotic protein found in diverse species. GAS41 is related to the AF-9 and ENL proteins, which are putative transcription factors in some acute leukemias,and interacts with a component of the nuclear matrix, NuMA, in interphase cells. GAS41 has a dotted staining pattern in interphase nuclei and a uniform distribution in mitotic cells. GAS41 is ubiquitously expressed, with the highest levels of expression in human brain. In neuroblastoma, GAS41 is located in the nucleoli, but not in the nucleoplasm. GAS41 also binds to the MLL fusion partner AF-10, which is involved in two distinct chromosomal translocations associated with hematologic malignancy. In addition, GAS41 interacts with INI1 (integrase interactor 1), which is a human homolog of the yeast Snf5 protein, a component of the SWI/SNF complex. The GAS41 gene maps to human chromosome 12q13-q15.Synonyms: GAS41, Glioma-amplified sequence 41, NuBI-1, NuBI1, NuMA-binding protein 1, YEATS domain-containing protein 4

Poids moléculaire: approx. 42 kDa

ID gène: 8089

NCBI Accession: NP_006521

UniProt: O95619