TRIM25 anticorps

N° du produit ABIN272231

Détail du produit anti-TRIM25 anticorps

Antigène: TRIM25 (Tripartite Motif Containing 25 (TRIM25))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIM25 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of EFP protein. (region surrounding Asp222)

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Pureté: > 95 % pure by SDS-PAGE

Information d'application

Indications d'application: ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: DO NOT FREEZE!

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur TRIM25

Antigène: TRIM25 (Tripartite Motif Containing 25 (TRIM25))

Autre désignation: TRIM25 / RNF147 (TRIM25 Produits)

Synonymes: anticorps zgc:55773, anticorps MGC130751, anticorps EFP, anticorps RNF147, anticorps Z147, anticorps ZNF147, anticorps AA960166, anticorps AL022677, anticorps Zfp147, anticorps Efp, anticorps Znf147, anticorps E3 ubiquitin/ISG15 ligase TRIM25, anticorps tripartite motif containing 25, anticorps E3 ubiquitin/ISG15 ligase TRIM25-like L homeolog, anticorps microRNA 3614, anticorps tripartite motif-containing 25, anticorps LOC100146440, anticorps trim25, anticorps LOC100490741.L, anticorps TRIM25, anticorps MIR3614, anticorps Trim25

Sujet: EFP (estrogen-responsive finger protein) is a transcription factor, the content of which is regulated by estrogen. It has been identified as a member of the RING finger family, a family of proteins containing a Zn2+ binding domain designated the C3HC4 or RING finger. EFP also contains two B box domains and a coiled-coil region (a transactivation domain), which are characteristic of a subgroup of the RING finger family. Estrogen regulates the growth, differentiation and function of target cells in a variety of tissues, however, few genes have been shown to be directly regulated by estrogen. It has been speculated that EFP may mediate estrogen activity in a signaling cascade in which estrogen-ER binding to the estrogen responsive element (ERE) downstream of the EFP gene upregulates EFP gene expression. The EFP gene product may then activate transcription of secondary estrogen responsive genes. Additional studies indicate that the EFP promoter may be regulated by multiple elements and their interacting factors.Synonyms: EFP, Estrogen-responsive finger protein, RING finger protein 147, Tripartite motif-containing protein 25, ZNF147, Zinc finger protein 147

Poids moléculaire: approx. 71 kDa

ID gène: 7706

NCBI Accession: NP_005073

UniProt: Q14258