SYT1 anticorps

N° du produit ABIN272235

Détail du produit anti-SYT1 anticorps

Antigène: SYT1 (Synaptotagmin I (SYT1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SYT1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of SYT protein. (region surrounding Ala7)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Pureté: > 95 % pure by SDS-PAGE

Information d'application

Indications d'application: ELISA: 1: 1000approx. 1: 5000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: DO NOT FREEZE!

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur SYT1

Antigène: SYT1 (Synaptotagmin I (SYT1))

Autre désignation: Synaptotagmin-1 (SYT1 Produits)

Synonymes: anticorps P65, anticorps SVP65, anticorps SYT, anticorps CG3139, anticorps D. Syt I, anticorps DSYT, anticorps DSYT2, anticorps DSypt, anticorps DSyt, anticorps Dmel\\CG3139, anticorps Droso1, anticorps Dsyt2, anticorps SYT I, anticorps SYT1, anticorps Syt, anticorps Syt 1, anticorps Syt I, anticorps Syt-1, anticorps SytI, anticorps dSYT, anticorps dsyt1, anticorps dsytI, anticorps l(2)23AB1, anticorps l(2)23Ba, anticorps l(2)k05909, anticorps syt, anticorps syt 1, anticorps syt I, anticorps syt-1, anticorps syt1, anticorps sytI, anticorps AW124717, anticorps G630098F17Rik, anticorps Syti, anticorps GB20036, anticorps DKFZP459P193, anticorps svp65, anticorps p65, anticorps wu:fj41c01, anticorps wu:fk56d05, anticorps zgc:92899, anticorps synaptotagmin 1, anticorps Synaptotagmin 1, anticorps synaptotagmin I, anticorps synaptotagmin-1, anticorps synaptotagmin, p65, anticorps synaptotagmin Ia, anticorps synaptotagmin 1 L homeolog, anticorps SYT1, anticorps Syt1, anticorps Tsp_06980, anticorps Tsp_08220, anticorps syt1, anticorps LOC100533340, anticorps syt1a, anticorps syt1.L

Sujet: The transcriptional coactivator SYT (synovial translocation protein) contains a conserved amino terminal SNH domain and a carboxy terminal QPGY domain, which is a functioning transcriptional activating sequence. Synovial sarcoma translocation (SSX) proteins, including SSX1-5, are transcriptional repressors that contain a repressor domain in their carboxy termini. SSX proteins are localized to the nucleus and expressed in testis and several types of cancers and, therefore, they are classified as C/T (cancer/testis) antigens. The t(x,18) translocation results in the fusion of the amino terminus of SYT to the carboxy terminus of either SSX1 or SSX2, both fusions result in the production of transcriptional activators. SYT-SSX chimeras are detected in most synovial sarcomas. Synovial sarcomas are responsible for up to 10 % of soft issue sarcomas and are histologically characterized as either biphasic or monophasic.Genetic analysis indicates that biphasic synovial sarcomas contain SYT-SSX1 fusions, whereas SYT-SSX2 fusions are found in monophasic synovial sarcomas, providing additional distinguishing characterization of these subtypes.Synonyms: SVP65, SYT, SYT1, Synaptotagmin I, Synaptotagmin1, SytI, p65

Poids moléculaire: approx. 45 kDa

ID gène: 6857

NCBI Accession: NP_001129277

UniProt: P21579

Pathways: Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport