NDUFA5 anticorps (AA 3-116)

N° du produit ABIN2726996

Détail du produit anti-NDUFA5 anticorps

Antigène: NDUFA5 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 5, 13kDa (NDUFA5))

Épitope: AA 3-116

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NDUFA5 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Attributs du produit: Homo sapiens NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13 kDa (NDUFA5), nuclear gene encoding mitochondrial protein

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogène: Human recombinant protein fragment corresponding to amino acids 3-116 of human NDUFA5(NP_004991) produced in HEK293T cell.

Clone: 1E8

Isotype: IgG1

Information d'application

Indications d'application: WB 1:2000, IF 1:100,

Commentaires:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur NDUFA5

Antigène: NDUFA5 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 5, 13kDa (NDUFA5))

Autre désignation: NDUFA5 (NDUFA5 Produits)

Synonymes: anticorps NADHUO, anticorps B13, anticorps CI-13KD-B, anticorps CI-13kB, anticorps NUFM, anticorps UQOR13, anticorps 2900002J19Rik, anticorps NADH:ubiquinone oxidoreductase subunit A5, anticorps NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, anticorps Ndufa5, anticorps NDUFA5

Sujet: The human NDUFA5 gene codes for the B13 subunit of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. The high degree of conservation of NDUFA5 extending to plants and fungi indicates its functional significance in the enzyme complex. The protein localizes to the inner mitochondrial membrane as part of the 7 component-containing, water soluble 'iron-sulfur protein' (IP) fraction of complex I, although its specific role is unknown. It is assumed to undergo post-translational removal of the initiator methionine and N-acetylation of the next amino acid. The predicted secondary structure is primarily alpha helix, but the carboxy-terminal half of the protein has high potential to adopt a coiled-coil form. The amino-terminal part contains a putative beta sheet rich in hydrophobic amino acids that may serve as mitochondrial import signal. Related pseudogenes have also been identified on four other chromosomes.

Poids moléculaire: 13.3 kDa

ID gène: 4698

NCBI Accession: NM_005000

HGNC: 4698