NFKBIZ anticorps

N° du produit ABIN2727234

Détail du produit anti-NFKBIZ anticorps

Antigène: NFKBIZ (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, zeta (NFKBIZ))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NFKBIZ est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Attributs du produit: Homo sapiens nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta (NFKBIZ), transcript variant 1

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogène: Full length human recombinant protein of human NFKBIZ (NP_113607) produced in E.coli.

Clone: 1E8

Isotype: IgG1

Information d'application

Indications d'application: WB 1:500, FLOW 1:100

Commentaires:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-NFKBIZ (ABIN2727234)

Zheng, Turton, Zhu, Li, Grindle, Annis, Lu, Drennan, Tweardy, Bharadwaj, Mosher, Rui: "A mix of S and ΔS variants of STAT3 enable survival of activated B-cell-like diffuse large B-cell lymphoma cells in culture." dans: Oncogenesis, Vol. 4, pp. e184, (2016) (PubMed).

Détails sur NFKBIZ

Antigène: NFKBIZ (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, zeta (NFKBIZ))

Autre désignation: NFKBIZ (NFKBIZ Produits)

Synonymes: anticorps RGD1310834, anticorps NFKBIZ, anticorps MAIL, anticorps AA408868, anticorps INAP, anticorps Mail, anticorps IKBZ, anticorps NFKB inhibitor zeta, anticorps nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta, anticorps nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta, anticorps Nfkbiz, anticorps NFKBIZ, anticorps nfkbiz

Sujet: This gene is a member of the ankyrin-repeat family and is induced by lipopolysaccharide (LPS). The C-terminal portion of the encoded product which contains the ankyrin repeats, shares high sequence similarity with the I kappa B family of proteins. The latter are known to play a role in inflammatory responses to LPS by their interaction with NF-B proteins through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production. Two transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 77.9 kDa

ID gène: 64332

NCBI Accession: NM_031419

HGNC: 64332

Pathways: Signalisation NF-kappaB