PBX1 anticorps

N° du produit ABIN2728334

Détail du produit anti-PBX1 anticorps

Antigène: PBX1 (Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PBX1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Attributs du produit: Homo sapiens pre-B-cell leukemia homeobox 1 (PBX1), transcript variant 1

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogène: Full length human recombinant protein of human PBX1(NP_002576) produced in HEK293 cell.

Clone: 4D1

Isotype: IgG1

Information d'application

Indications d'application: WB 1:2000, IF 1:100, FLOW 1:100,

Commentaires:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur PBX1

Antigène: PBX1 (Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))

Autre désignation: PBX1 (PBX1 Produits)

Synonymes: anticorps fi29e01, anticorps pbx1b, anticorps wu:fi29e01, anticorps zgc:55265, anticorps 2310056B04Rik, anticorps AI848790, anticorps AU015730, anticorps D230003C07Rik, anticorps Pbx-1, anticorps Pbx1a, anticorps Pbx1b, anticorps PBX1A, anticorps Xpbx1, anticorps Xpbx1b, anticorps PBX homeobox 1, anticorps pre-B-cell leukemia homeobox 1a, anticorps pre B cell leukemia homeobox 1, anticorps pre-B-cell leukemia homeobox 1 S homeolog, anticorps PBX1, anticorps pbx1a, anticorps Pbx1, anticorps pbx1.S

Sujet: This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, t(1,19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 46.4 kDa

ID gène: 5087

NCBI Accession: NM_002585

HGNC: 5087