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SIRT6 anticorps (AA 88-352)

SIRT6 Reactivité: Humain WB, IF Hôte: Souris Monoclonal 1G3 unconjugated
N° du produit ABIN2732083
  • Antigène Voir toutes SIRT6 Anticorps
    SIRT6 (Sirtuin 6 (SIRT6))
    Épitope
    • 16
    • 15
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 88-352
    Reactivité
    • 92
    • 31
    • 16
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 88
    • 12
    • 2
    Souris
    Clonalité
    • 83
    • 19
    Monoclonal
    Conjugué
    • 53
    • 12
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SIRT6 est non-conjugé
    Application
    • 83
    • 40
    • 36
    • 14
    • 14
    • 11
    • 8
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Attributs du produit
    Homo sapiens sirtuin 6 (SIRT6), transcript variant 1
    Purification
    Purified from mouse ascites fluids by affinity chromatography
    Immunogène
    Human recombinant protein fragment corresponding to amino acids 88-352 of human SIRT6(NP_057623) produced in E.coli.
    Clone
    1G3
    Isotype
    IgG1
    Top Product
    Discover our top product SIRT6 Anticorps primaire
  • Indications d'application
    WB 1:500~2000, IF 1:100,
    Commentaires

    The concentration of the product may vary between diferrent lots.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5-1.0 mg/mL
    Buffer
    PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
  • Sugatani, Agapova, Malluche, Hruska: "SIRT6 deficiency culminates in low-turnover osteopenia." dans: Bone, Vol. 81, pp. 168-77, (2015) (PubMed).

  • Antigène
    SIRT6 (Sirtuin 6 (SIRT6))
    Autre désignation
    SIRT6 (SIRT6 Produits)
    Synonymes
    anticorps 2810449N18Rik, anticorps AI043036, anticorps Sir2l6, anticorps SIR2L6, anticorps zgc:86729, anticorps sirtuin 6, anticorps sirtuin 6 S homeolog, anticorps Sirt6, anticorps SIRT6, anticorps sirt6.S, anticorps sirt6
    Sujet
    This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. Alternative splicing results in multiple transcript variants.
    Poids moléculaire
    38.9 kDa
    ID gène
    51548
    NCBI Accession
    NM_016539
    HGNC
    51548
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