hCoV-OC43 Spike anticorps (AA 15-344) (Biotin)

N° du produit ABIN2754657

Détail du produit anti-hCoV-OC43 Spike anticorps (Biotin)

Antigène: hCoV-OC43 Spike (HCoV-OC43 S) (Coronavirus OC43 Spike Protein (HCoV-OC43 S))

Épitope: AA 15-344

Reactivité: Human Coronavirus OC43 (HCoV-OC43)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp hCoV-OC43 Spike est conjugé à/à la Biotin

Application: ELISA

Purification: Caprylic Acid Ammonium Sulfate Precipitation

Immunogène: Recombinant Human coronavirus OC43 Spike glycoprotein protein(15-344aa)

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C/-80 °C

Détails sur hCoV-OC43 Spike

Antigène: hCoV-OC43 Spike (HCoV-OC43 S) (Coronavirus OC43 Spike Protein (HCoV-OC43 S))

Autre désignation: OC43 Spike Glycoprotein (HCoV-OC43 S Produits)

Classe de substances: Viral Protein

Sujet: S1 attaches the virion to the cell membrane by interacting with sialic acid-containing cell receptors, initiating the infection. S2 is a class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.

UniProt: P36334