DHX58 anticorps (N-Term)

N° du produit ABIN501562

Détail du produit anti-DHX58 anticorps

Antigène: DHX58 (DEXH (Asp-Glu-X-His) Box Polypeptide 58 (DHX58))

Épitope: N-Term

Reactivité: Humain, Rat, Souris, Cheval, Cobaye, Boeuf (Vache), Chien, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DHX58 est non-conjugé

Application: Western Blotting (WB)

Séquence: AYVAKRHLET VDGAKVVVLV NRVHLVTQHG EEFRRMLDGR WTVTTLSGDM

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 91%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against DHX58. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human DHX58

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 678 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur DHX58

Antigène: DHX58 (DEXH (Asp-Glu-X-His) Box Polypeptide 58 (DHX58))

Autre désignation: DHX58 (DHX58 Produits)

Synonymes: anticorps MGC82787, anticorps DHX58, anticorps lgp2, anticorps D11LGP2, anticorps D11lgp2e, anticorps LGP2, anticorps RLR-3, anticorps B430001I08Rik, anticorps D11Lgp2e, anticorps LPG2, anticorps Lgp2, anticorps RGD1310093, anticorps DEXH-box helicase 58 L homeolog, anticorps DExH-box helicase 58, anticorps probable ATP-dependent RNA helicase DHX58, anticorps DEXH (Asp-Glu-X-His) box polypeptide 58, anticorps DEXH-box helicase 58, anticorps dhx58.L, anticorps DHX58, anticorps dhx58, anticorps LOC100566102, anticorps Dhx58

Sujet: DHX58 is the negative regulator of host innate immune defense against viruses. The repressor domain of DHX58 interacts with DDX58 and negatively regulates DDX58-mediated signaling. Binds dsRNA produced during viral replication, in particuliar HCV RNA. Bin
Alias Symbols: D11LGP2, D11lgp2e, LGP2
Protein Interaction Partner: USP21, APP, UBD, NKRF, CDKN2AIP, AGO2, STAU2, DICER1, DHX30, XRN2, STAU1, EIF2AK2, EIF6, AP2B1,
Protein Size: 678

Poids moléculaire: 76 kDa

ID gène: 79132

NCBI Accession: NM_024119, NP_077024

UniProt: Q96C10