EPB41 anticorps (N-Term)

N° du produit ABIN2775561

Détail du produit anti-EPB41 anticorps

Antigène: EPB41 (Erythrocyte Membrane Protein Band 4.1 (Elliptocytosis 1, RH-Linked) (EPB41))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Cheval, Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPB41 est non-conjugé

Application: Western Blotting (WB)

Séquence: SESRGLSRLF SSFLKRPKSQ VSEEEGKEVE SDKEKGEGGQ KEIEFGTSLD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against EPB41. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human EPB41

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 775 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur EPB41

Antigène: EPB41 (Erythrocyte Membrane Protein Band 4.1 (Elliptocytosis 1, RH-Linked) (EPB41))

Autre désignation: EPB41 (EPB41 Produits)

Synonymes: anticorps P4.1R, anticorps epb41, anticorps wu:fb70c02, anticorps EPB41, anticorps el1, anticorps 4.1r, anticorps 4.1R, anticorps EL1, anticorps HE, anticorps AI415518, anticorps D4Ertd442e, anticorps Elp-1, anticorps Elp1, anticorps Epb41, anticorps mKIAA4056, anticorps erythrocyte membrane protein band 4.1b, anticorps erythrocyte membrane protein band 4.1, anticorps erythrocyte membrane protein band 4.1 L homeolog, anticorps epb41b, anticorps EPB41, anticorps epb41, anticorps epb41.L, anticorps Epb41

Sujet: Elliptocytosis is a hematologic disorder characterized by elliptically shaped erythrocytes and a variable degree of hemolytic anemia. Inherited as an autosomal dominant, elliptocytosis results from mutation in any one of several genes encoding proteins of the red cell membrane skeleton. The form discussed here is the one found in the 1950s to be linked to Rh blood group and more recently shown to be caused by a defect in protein 4.1. 'Rh-unlinked' forms of elliptocytosis are caused by mutation in the alpha-spectrin gene, the beta-spectrin gene, or the band 3 gene.Elliptocytosis is a hematologic disorder characterized by elliptically shaped erythrocytes and a variable degree of hemolytic anemia. Inherited as an autosomal dominant, elliptocytosis results from mutation in any one of several genes encoding proteins of the red cell membrane skeleton. The form discussed here is the one found in the 1950s to be linked to Rh blood group and more recently shown to be caused by a defect in protein 4.1. 'Rh-unlinked' forms of elliptocytosis are caused by mutation in the alpha-spectrin gene (MIM 182860), the beta-spectrin gene (MIM 182870), or the band 3 gene (MIM 109270).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-95 BM465039.1 1-95 96-2238 J03796.1 40-2182 2239-2780 AL833483.1 1799-2340 2781-2943 BU184161.1 560-722 2944-3952 AL833483.1 2504-3512 3953-4352 BM997767.1 226-625 4353-4796 BE257308.1 115-558 4797-5656 BC009063.1 442-1301 5657-6064 BM740451.1 1-408 c
Alias Symbols: 4.1R, EL1, HE
Protein Interaction Partner: CLNS1A, ZCCHC10, RWDD2B, CALM, UBC, FN1, Htt, MACROD1, C2CD2L, CENPJ, TJP2, EIF3G, SMAD3, SEC14L1, YWHAB, DLG1, KPNA2, CASK, GDI1, U2AF2, U2AF1, TUBA4A, TPM1, FKBP2, SPTB, SPTAN1, SPTBN1, EPB42, PRKCB, NUMA1, MYL1, YWHAQ, EGFR, DRD3, DRD2, CRYAB, BCAM, GY
Protein Size: 775

Poids moléculaire: 85 kDa

ID gène: 2035

NCBI Accession: NM_203343, NP_976218

UniProt: Q4VB86