EPB41 anticorps (pTyr418, pTyr660)

N° du produit ABIN7139042

Détail du produit anti-EPB41 anticorps

Antigène: EPB41 (Erythrocyte Membrane Protein Band 4.1 (Elliptocytosis 1, RH-Linked) (EPB41))

Épitope: pTyr418, pTyr660

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPB41 est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée: Humain, Souris

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogène: Peptide sequence around phosphorylation site of tyrosine 660/418 (N-I-Y(p)-I-R)derived from Human EPB41.

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:1000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur EPB41

Antigène: EPB41 (Erythrocyte Membrane Protein Band 4.1 (Elliptocytosis 1, RH-Linked) (EPB41))

Autre désignation: EPB41 (EPB41 Produits)

Synonymes: anticorps P4.1R, anticorps epb41, anticorps wu:fb70c02, anticorps EPB41, anticorps el1, anticorps 4.1r, anticorps 4.1R, anticorps EL1, anticorps HE, anticorps AI415518, anticorps D4Ertd442e, anticorps Elp-1, anticorps Elp1, anticorps Epb41, anticorps mKIAA4056, anticorps erythrocyte membrane protein band 4.1b, anticorps erythrocyte membrane protein band 4.1, anticorps erythrocyte membrane protein band 4.1 L homeolog, anticorps epb41b, anticorps EPB41, anticorps epb41, anticorps epb41.L, anticorps Epb41

Sujet:

Background:

Elliptocytosis is a hematologic disorder characterized by elliptically shaped erythrocytes and a variable degree of hemolytic anemia. Inherited as an autosomal dominant, elliptocytosis results from mutation in any one of several genes encoding proteins of the red cell membrane skeleton. The form discussed here is the one found in the 1950s to be linked to Rh blood group and more recently shown to be caused by a defect in protein 4.1. 'Rh-unlinked' forms of elliptocytosis are caused by mutation in the alpha-spectrin gene, the beta-spectrin gene, or the band 3 gene.

Conboy J.G., Proc. Natl. Acad. Sci. U.S.A. 83:9512-9516(1986).
Tang T.K., Adv. Exp. Med. Biol. 241:81-95(1988).
Tang T.K., Proc. Natl. Acad. Sci. U.S.A. 85:3713-3717(1988).

Aliases: 4.1R antibody, 41_HUMAN antibody, Band 4.1 antibody, E41P antibody, EL 1 antibody, EL1 antibody, EL1 gene antibody, Elliptocytosis 1 antibody, Elliptocytosis 1 RH linked antibody, EPB 4.1 antibody, EPB 41 antibody, EPB4.1 antibody, Epb41 antibody, Erythrocyte membrane protein band 4.1 (elliptocytosis 1 RH linked) antibody, Erythrocyte membrane protein band 4.1 antibody, Erythrocyte surface protein band 4.1 antibody, HE antibody, P4.1 antibody, Protein 4.1 antibody, Protein 4.1, red blood cell type antibody

UniProt: P11171