SRY anticorps (Middle Region)

N° du produit ABIN2776027

Détail du produit anti-SRY anticorps

Antigène: SRY (Sex Determining Region Y (SRY))

Épitope: Middle Region

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SRY est non-conjugé

Application: Western Blotting (WB)

Séquence: SEVQLDNRLY RDDCTKATHS RMEHQLGHLP PINAASSPQQ RDRYSHWTKL

Homologie: Human: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against SRY. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SRY

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 204 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SRY

Antigène: SRY (Sex Determining Region Y (SRY))

Autre désignation: SRY (SRY Produits)

Synonymes: anticorps SRXX1, anticorps SRXY1, anticorps TDF, anticorps TDY, anticorps SRYGENE, anticorps Sry1, anticorps Sry3BI, anticorps Tdf, anticorps Tdy, anticorps SRY, anticorps sex determining region Y, anticorps sex determining region of Chr Y, anticorps SRY, anticorps Sry

Sujet: SRY is an intronless gene that encodes for a transcription factor, which is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor(TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome), translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome.This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome), translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: TDF, TDY, SRXX1, SRXY1
Protein Interaction Partner: Olig2, Utf1, Tcf12, Sp1, Pou3f3, Pax3, Jun, Hhex, Egr2, Dlx5, Cebpa, WDR5, SMAD3, HDAC3, KPNB1, EP300, Xpo4, ZNF208, SLC9A3R2, AR,
Protein Size: 204

Poids moléculaire: 24 kDa

ID gène: 6736

NCBI Accession: NM_003140, NP_003131

UniProt: Q05066