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KCNJ11 anticorps (Middle Region)
KCNJ11
Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio)
WB
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN2776174
Détail du produit anti-KCNJ11 anticorps
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Antigène
Voir toutes KCNJ11 Anticorps
KCNJ11
(Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11))
Épitope
Tous les épitopes à travers KCNJ11 Anticorps.
Middle Region
Reactivité
Toutes les réactivités sur KCNJ11 Anticorps
Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio)
Hôte
Toutes les hôtes sur KCNJ11 Anticorps
Lapin
Clonalité
Toutes les clonalités sur KCNJ11 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers KCNJ11 Anticorps
Cet anticorp KCNJ11 est non-conjugé
Application
Tous les applications à travers KCNJ11 Anticorps.
Western Blotting (WB)
Séquence
SMIISATIHM QVVRKTTSPE GEVVPLHQVD IPMENGVGGN SIFLVAPLII
Homologie
Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%
Attributs du produit
This is a rabbit polyclonal antibody against KCNJ11. It was validated on Western Blot.
Purification
Affinity Purified
Immunogène
The immunogen is a synthetic peptide directed towards the middle region of HUMAN KCNJ11
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Discover our top product KCNJ11 Anticorps primaire
Alternatives
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anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11) (Center) antibody
KCNJ11
Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Porc
WB, IHC, IF, IC
Hôte: Lapin
Polyclonal
unconjugated
Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeat freeze-thaw cycles.
Stock
-20 °C
Stockage commentaire
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Détails sur KCNJ11
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Antigène
KCNJ11
(Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11))
Autre désignation
KCNJ11 (KCNJ11 Produits )
Synonymes
anticorps kir6.2, anticorps Kir6.2, anticorps mBIR, anticorps BIR, anticorps HHF2, anticorps IKATP, anticorps KIR6.2, anticorps PHHI, anticorps TNDM3, anticorps potassium voltage-gated channel subfamily J member 11, anticorps potassium inwardly-rectifying channel, subfamily J, member 11, anticorps potassium inwardly rectifying channel, subfamily J, member 11, anticorps KCNJ11, anticorps kcnj11, anticorps Kcnj11
Sujet
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR. Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), an autosomal recessive disorder characterized by unregulated insulin secretion. Defects in this gene may also contribute to autosomal dominant non-insulin-dependent diabetes mellitus type II (NIDDM), transient neonatal diabetes mellitus type 3 (TNDM3), and permanent neonatal diabetes mellitus (PNDM). Alias Symbols: BIR, HHF2, IKATP, KIR6.2, PHHI, TNDM3 Protein Interaction Partner: YWHAB, UBC, ABCC9, AP2M1, KCNJ8, KCNJ2, ABCC8, LDHA, Protein Size: 303
Poids moléculaire
33 kDa
ID gène
3767
NCBI Accession
NM_001166290 , NP_001159762
Pathways
Negative Regulation of Hormone Secretion
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