FXYD5 anticorps (Middle Region)
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- Antigène Voir toutes FXYD5 Anticorps
- FXYD5 (FXYD Domain Containing Ion Transport Regulator 5 (FXYD5))
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Épitope
- Middle Region
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp FXYD5 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- SERPSPSTDV QTDPQTLKPS GFHEDDPFFY DEHTLRKRGL LVAAVLFITG
- Homologie
- Human: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against FXYD5. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human FXYD5
- Top Product
- Discover our top product FXYD5 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 178 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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FXYD5 modulates Na+ absorption and is increased in cystic fibrosis airway epithelia." dans: American journal of physiology. Lung cellular and molecular physiology, Vol. 294, Issue 4, pp. L654-64, (2008) (PubMed).
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FXYD5 modulates Na+ absorption and is increased in cystic fibrosis airway epithelia." dans: American journal of physiology. Lung cellular and molecular physiology, Vol. 294, Issue 4, pp. L654-64, (2008) (PubMed).
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- Antigène
- FXYD5 (FXYD Domain Containing Ion Transport Regulator 5 (FXYD5))
- Autre désignation
- FXYD5 (FXYD5 Produits)
- Synonymes
- anticorps FXYD5, anticorps DYSAD, anticorps IWU1, anticorps KCT1, anticorps OIT2, anticorps PRO6241, anticorps RIC, anticorps EF-8, anticorps Oit2, anticorps FXYD domain containing ion transport regulator 5, anticorps FXYD domain-containing ion transport regulator 5, anticorps FXYD5, anticorps Fxyd5
- Sujet
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FXYD5 is a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. This gene product, FXYD5, has not been characterized as a protein. This reference sequence was derived from AF161462.1 and ESTs, validated by multiple replicate ESTs and human genomic sequence. This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. This gene product, FXYD5, has not been characterized as a protein. Two transcript variants have been found for this gene, and they are both predicted to encode the same protein. [RefSeq curation by Kathleen J. Sweadner, Ph.D., sweadner@helix.mgh.harvard.edu.].
Alias Symbols: HSPC113, IWU-1, IWU1, KCT1, OIT2, PRO6241, RIC, dysad, DYSAD
Protein Interaction Partner: UBC,
Protein Size: 178 - Poids moléculaire
- 19 kDa
- ID gène
- 53827
- NCBI Accession
- NM_014164, NP_054883
- UniProt
- Q96DB9
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