Prothrombin anticorps (Middle Region)

N° du produit ABIN2776976

Cet anticorps Lapin Polyclonal détecte spécifiquement Prothrombin dans WB et IHC. Il présente une réactivité envers Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Mouton et Poisson zèbre (Danio rerio).

Aperçu rapide pour Prothrombin anticorps (Middle Region) (ABIN2776976)

Antigène: Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Mouton, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Prothrombin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Prothrombin anticorps

Épitope: Middle Region

Séquence: ISDRWVLTAA HCLLYPPWDK NFTENDLLVR IGKHSRTRYE RNIEKISMLE

Homologie: Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 77%

Attributs du produit: This is a rabbit polyclonal antibody against F2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human F2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 622 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Prothrombin

Antigène: Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))

Autre désignation: F2

Sujet: Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life.Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: PT
Protein Interaction Partner: ST13, FN1, DDIT3, ALB, F11, PROZ, ITGA2B, SERPING1, HGFAC, AKR7A2, CPB2, F2RL3, F2RL2, SERPINA5, SERPINB8, AANAT, F2RL1, F9, F8, GP1BA, KNG1, F5, C6, PLAU, THBS1, THBD, F2R, SERPINE2, F2, PROS1, AMBP, PROC, GP5, SERPINE1, SERPINB6, SPP1, IGFBP5, IGFBP3, S
Protein Size: 622

Poids moléculaire: 70 kDa

ID gène: 2147

NCBI Accession: NM_000506, NP_000497

UniProt: P00734

Pathways: Système du Complément, Peptide Hormone Metabolism, Regulation of G-Protein Coupled Receptor Protein Signaling