PTGS1 anticorps (N-Term)

N° du produit ABIN2777018

Détail du produit anti-PTGS1 anticorps

Antigène: PTGS1 (Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Mouton, Boeuf (Vache), Cheval, Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTGS1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: LDRYQCDCTR TGYSGPNCTI PGLWTWLRNS LRPSPSFTHF LLTHGRWFWE

Homologie: Cow: 79%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Rat: 93%, Sheep: 79%

Attributs du produit: This is a rabbit polyclonal antibody against PTGS1. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PTGS1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 599 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PTGS1

Antigène: PTGS1 (Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1))

Autre désignation: PTGS1 (PTGS1 Produits)

Synonymes: anticorps COX-1, anticorps cox-1, anticorps PTGS1, anticorps Ptgs1, anticorps COX1, anticorps Cox-1, anticorps Cox-3, anticorps PGHS-1, anticorps PHS 1, anticorps Pghs1, anticorps Cox1, anticorps Cox3, anticorps cox1, anticorps zCOX-1, anticorps COX3, anticorps PCOX1, anticorps PES-1, anticorps PGG/HS, anticorps PGHS1, anticorps PHS1, anticorps PTGHS, anticorps COX-3, anticorps prostaglandin-endoperoxide synthase 1, anticorps cyclooxygenase-1, anticorps prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase), anticorps prostaglandin-endoperoxide synthase 1 S homeolog, anticorps PTGS1, anticorps cox-1, anticorps Ptgs1, anticorps ptgs1, anticorps ptgs1.S

Sujet: Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis.Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis. Alternative splicing of this gene generates two transcript variants. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors.
Alias Symbols: COX1, COX3, PCOX1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS
Protein Interaction Partner: FBXO6, PTGS2, NCL, CAV2, CAV1, PTGIS, Dlg4, PTGS1, NUCB1,
Protein Size: 599

Poids moléculaire: 69 kDa

ID gène: 5742

NCBI Accession: NM_000962, NP_000953

UniProt: P23219