NFYB anticorps (Middle Region)

N° du produit ABIN486823

Détail du produit anti-NFYB anticorps

Antigène: NFYB (Nuclear Transcription Factor Y, beta (NFYB))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Porc, Lapin, Cobaye, Cheval, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NFYB est non-conjugé

Application: Western Blotting (WB)

Séquence: EAMKGEKGIG GAVTATDGLS EELTEEAFTN QLPAGLITTD GQQQNVMVYT

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 91%

Attributs du produit: This is a rabbit polyclonal antibody against NFYB. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human NFYB

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 207 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur NFYB

Antigène: NFYB (Nuclear Transcription Factor Y, beta (NFYB))

Autre désignation: NFYB (NFYB Produits)

Synonymes: anticorps CBF-A, anticorps CBF-B, anticorps HAP3, anticorps NF-YB, anticorps NFYB, anticorps nfyb, anticorps zgc:110533, anticorps zgc:110552, anticorps hap3, anticorps cbf-a, anticorps cbf-b, anticorps CBFB, anticorps Nfya, anticorps AA985999, anticorps Cbf-A, anticorps nuclear transcription factor Y subunit beta, anticorps nuclear transcription factor Y subunit beta L homeolog, anticorps nuclear transcription factor Y, beta b, anticorps nuclear transcription factor Y, beta a, anticorps nuclear transcription factor-Y beta, anticorps NFYB, anticorps nfyb.L, anticorps nfybb, anticorps nfyba, anticorps nfyb, anticorps Nfyb

Sujet: NFYB is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence, protein sequence alignments and experiments with mutants.
Alias Symbols: CBF-A, CBF-B, HAP3, NF-YB
Protein Interaction Partner: AGTRAP, POLE4, DRAP1, NFYA, LYN, CDK2, CCNE1, CCNA2, TP53, SMYD3, NFYC, MAOB, UBC, CREBBP, SP1, HDAC1, EP300, KAT2B, TP73, TAF12, TAF11, TAF6, GRB2, YBX3, CEBPZ, C1QBP, TBP, CIITA, CNTN2, MYC, ELF1, YBX1,
Protein Size: 207

Poids moléculaire: 23 kDa

ID gène: 4801

NCBI Accession: NM_006166, NP_006157

UniProt: P25208

Pathways: Regulation of Lipid Metabolism by PPARalpha