NR0B1 anticorps (Middle Region)

N° du produit ABIN2777385

Détail du produit anti-NR0B1 anticorps

Antigène: NR0B1 (Nuclear Receptor Subfamily 0, Group B, Member 1 (NR0B1))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Cheval, Boeuf (Vache), Cobaye, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NR0B1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: QAIKCFLSKC WSLNISTKEY AYLKGTVLFN PDVPGLQCVK YIQGLQWGTQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against NR0B1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human NR0B1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 470 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur NR0B1

Antigène: NR0B1 (Nuclear Receptor Subfamily 0, Group B, Member 1 (NR0B1))

Autre désignation: NR0B1 (NR0B1 Produits)

Synonymes: anticorps DAX, anticorps NR0B1, anticorps dax1, anticorps AHC, anticorps AHCH, anticorps AHX, anticorps DAX-1, anticorps DAX1, anticorps DSS, anticorps GTD, anticorps HHG, anticorps NROB1, anticorps SRXY2, anticorps Ahc, anticorps Ahch, anticorps Dax1, anticorps nuclear receptor subfamily 0 group B member 1, anticorps nuclear receptor subfamily 0, group B, member 1, anticorps nuclear receptor subfamily 0 group B member 1 L homeolog, anticorps NR0B1, anticorps nr0b1, anticorps nr0b1.L, anticorps Nr0b1

Sujet: NR0B1 is a protein that contains a DNA-binding domain. The protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in its gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AHC, AHCH, AHX, DAX-1, DAX1, DSS, GTD, HHG, NROB1, SRXY2
Protein Interaction Partner: NR5A1, ESRRG, RORA, RNF31, UBC, NR3C1, ESRRA, SNW1, PPARG, POU5F1, PGR, AR, COPS2, NRIP1, ESR2, SREBF1, ESR1,
Protein Size: 470

Poids moléculaire: 52 kDa

ID gène: 190

NCBI Accession: NM_000475, NP_000466

UniProt: Q9BG96

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling