Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (N-Term) anticorps

N° du produit ABIN2777593

Détail du produit

Antigène: Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB)

Séquence: AAGFGRCCRV LRSISRFHWR SQHTKANRQR EPGLGFSFEF TEQQKEFQAT

Homologie: Cow: 92%, Horse: 92%, Human: 100%, Mouse: 91%, Rat: 91%

Attributs du produit: This is a rabbit polyclonal antibody against ACADM. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ACADM

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 421 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détail du antigène

Antigène: Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial

Autre désignation: ACADM

Synonymes: anticorps ACAD1, anticorps MCAD, anticorps MCADH, anticorps AU018656, anticorps acyl-CoA dehydrogenase medium chain, anticorps acyl-Coenzyme A dehydrogenase, medium chain, anticorps acyl-CoA dehydrogenase, C-4 to C-12 straight chain, anticorps ACADM, anticorps Acadm

Sujet: ACADM Is the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Clinical phenotypes are associated with ACADM hereditary deficiency.This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ACAD1, MCAD, MCADH
Protein Interaction Partner: SUMO2, SUMO3, UBC, MDM2, STRAP, HDAC1, UBD, CUL3, SUMO4, CALM1, USP50, USP20, ACADM,
Protein Size: 421

Poids moléculaire: 46 kDa

ID gène: 34

NCBI Accession: NM_000016, NP_000007

UniProt: P11310