KCNJ5 anticorps (Middle Region)

N° du produit ABIN2778095

Détail du produit anti-KCNJ5 anticorps

Antigène: KCNJ5 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 5 (KCNJ5))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Cheval, Poisson zèbre (Danio rerio), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNJ5 est non-conjugé

Application: Western Blotting (WB)

Séquence: SGFALKRNVL GRNLTANDPS QEYVASEGEE DPEVEFLKSL TTKQKQKLLR

Homologie: Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CIR. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human CIR

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 324 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur KCNJ5

Antigène: KCNJ5 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 5 (KCNJ5))

Autre désignation: CIR (KCNJ5 Produits)

Synonymes: anticorps CIR, anticorps GIRK4, anticorps KATP1, anticorps KIR3.4, anticorps LQT13, anticorps Kir3.4, anticorps GIRK-4, anticorps KATP-1, anticorps potassium voltage-gated channel subfamily J member 5, anticorps potassium inwardly-rectifying channel, subfamily J, member 5, anticorps KCNJ5, anticorps Kcnj5

Sujet: CIR may modulate splice site selection during alternative splicing of pre-mRNAs. CIR regulates transcription and acts as corepressor for RBPSUH by recruiting RBPSUH to the Sin3-histone deacetylase complex (HDAC). CIR is also required for RBPSUH-mediated repression of transcription.
Alias Symbols: CIR
Protein Interaction Partner: CEP76, NEK6, U2AF1, SRSF2, SRSF1, RP9, HDAC2, SAP30, SNW1, TCEA1, NCOR2, RBPJ,
Protein Size: 324

Poids moléculaire: 34 kDa

ID gène: 9541

UniProt: Q86X95

Pathways: Signalisation Notch