SUPT5H anticorps (Middle Region)

N° du produit ABIN404918

Détail du produit anti-SUPT5H anticorps

Antigène: SUPT5H (Transcription Elongation Factor SPT5 (SUPT5H))

Épitope: Middle Region

Reactivité: Humain, Souris, Chien, Boeuf (Vache), Rat, Lapin, Cheval, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SUPT5H est non-conjugé

Application: Western Blotting (WB)

Séquence: FEDQPEGIDL EVVTESTGKE REHNFQPGDN VEVCEGELIN LQGKILSVDG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against SUPT5H. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SUPT5H

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1087 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-SUPT5H (ABIN404918)

Ueki, Lin, Senoo, Ebihara, Agata, Onji, Saheki, Kawai, Mukherjee, Reichenberger, Olsen: "Increased myeloid cell responses to M-CSF and RANKL cause bone loss and inflammation in SH3BP2 "cherubism" mice." dans: Cell, Vol. 128, Issue 1, pp. 71-83, (2007) (PubMed).

Amir-Zilberstein, Ainbinder, Toube, Yamaguchi, Handa, Dikstein: "Differential regulation of NF-kappaB by elongation factors is determined by core promoter type." dans: Molecular and cellular biology, Vol. 27, Issue 14, pp. 5246-59, (2007) (PubMed).

Détails sur SUPT5H

Antigène: SUPT5H (Transcription Elongation Factor SPT5 (SUPT5H))

Autre désignation: SUPT5H (SUPT5H Produits)

Synonymes: anticorps SPT5, anticorps SPT5H, anticorps Tat-CT1, anticorps F13P17.5, anticorps F13P17_5, anticorps Spt5, anticorps etID10129.15, anticorps etID37101.15, anticorps fb37g01, anticorps fb95e05, anticorps fog, anticorps foggy, anticorps wu:fb37g01, anticorps wu:fb95e05, anticorps wu:fc10f02, anticorps spt5, anticorps spt5h, anticorps tat-ct1, anticorps CG7626, anticorps DSIF, anticorps Dmel\\CG7626, anticorps Dspt5, anticorps dDSIF, anticorps dSpt5, anticorps CaO19.1453, anticorps SPT5 homolog, DSIF elongation factor subunit, anticorps transcription elongation factor SPT5, anticorps Transcription elongation factor Spt5, anticorps transcription elongation factor Spt5, anticorps transcription elongation factor spt5, anticorps hypothetical protein, anticorps SPT5 homolog, DSIF elongation factor subunit S homeolog, anticorps CG7626 gene product from transcript CG7626-RA, anticorps Transcription elongation factor SPT5, anticorps transcription elongation factor, anticorps SUPT5H, anticorps LOC413814, anticorps AT2G34210, anticorps spt5, anticorps MGYG_08422, anticorps TERG_05483, anticorps PGTG_18458, anticorps supt5h, anticorps Supt5h, anticorps supt5h.S, anticorps Spt5, anticorps spt-5, anticorps SPT5

Sujet: SUPT5H and its binding partner regulate transcriptional elongation by RNA polymerase II. SPT4 and SPT5 are involved in both 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole (DRB)-mediated transcriptional inhibition and the activation of transcriptional elongation by the human immunodeficiency virus type 1 (HIV-1) Tat protein.
Alias Symbols: FLJ34157, SPT5, SPT5H, Tat-CT1
Protein Interaction Partner: POLR2A, BRCA1, UBC, RNF2, SAMHD1, GANAB, SWAP70, PAICS, CARM1, FARSB, SEC24C, RANBP3, CSDE1, SF1, SET, PLOD2, MSH2, MSH6, GART, XRCC6, ATP6V1B2, SOX2, LMNA, CDK9, CCNT2, CCNT1, tat, NSMF, FN1, CSNK2A1, SIK1, ZNF512B, LMAN2, ZFYVE9, SNX4, SUPT4H1, POLR2C,
Protein Size: 1087

Poids moléculaire: 121 kDa

ID gène: 6829

NCBI Accession: NM_003169, NP_003160

UniProt: O00267