KHDRBS3 anticorps (C-Term)

N° du produit ABIN2778997

Détail du produit anti-KHDRBS3 anticorps

Antigène: KHDRBS3 (KH Domain Containing, RNA Binding, Signal Transduction Associated 3 (KHDRBS3))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KHDRBS3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: EQSYDSYDNS YSTPAQSGAD YYDYGHGLSE ETYDSYGQEE WTNSRHKAPS

Homologie: Cow: 100%, Dog: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against KHDRBS3. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human KHDRBS3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 346 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur KHDRBS3

Antigène: KHDRBS3 (KH Domain Containing, RNA Binding, Signal Transduction Associated 3 (KHDRBS3))

Autre désignation: KHDRBS3 (KHDRBS3 Produits)

Synonymes: anticorps KHDRBS3, anticorps T-STAR, anticorps Etle, anticorps SALP, anticorps SLM-2, anticorps SLM2, anticorps TSTAR, anticorps etoile, anticorps Slm2, anticorps KH domain containing, RNA binding, signal transduction associated 3, anticorps KH RNA binding domain containing, signal transduction associated 3, anticorps KHDRBS3, anticorps Khdrbs3

Sujet: As a RNA-binding protein, KHDRBS3 plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. KHDRBS3 may play a role as a negative regulator of cell growth. It inhibits cell proliferation and involved in splice site selection of vascular endothelial growth factor. It induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. RNA-binding abilities are down-regulated by tyrosine kinase PTK6. It also involved in post-transcriptional regulation of HIV-1 gene expression.
Alias Symbols: Etle, SALP, SLM2, SLM-2, TSTAR, T-STAR, etoile
Protein Interaction Partner: YTHDC1, DMRT3, MARK4, NCOA5, PRPF31, BAHD1, KHDRBS3, INPP5D, UBC, BMI1, NELFB, RBM7, PSMF1, SIAH1, HNRNPK, KHDRBS2, CCDC33, PTBP2, U2AF2, KHDRBS1, SNRPC, HNRNPC, FUS, FBXO32, SERPINB5, RBBP6, CACNA1A, RPAP2, ZNF408, LNX1, SGSM2, SRSF9, NUDT18, PRMT1, RBMY
Protein Size: 346

Poids moléculaire: 38 kDa

ID gène: 10656

NCBI Accession: NM_006558, NP_006549

UniProt: O75525