TCF7L1 anticorps (N-Term)

N° du produit ABIN2779272

L’anticorps Lapin Polyclonal anti-TCF7L1 a été validé pour WB et IHC. Il convient pour détecter TCF7L1 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien et Cobaye.

Aperçu rapide pour TCF7L1 anticorps (N-Term) (ABIN2779272)

Antigène: TCF7L1 (Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TCF7L1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-TCF7L1 anticorps

Épitope: N-Term

Séquence: NDELIPFQDE GGEEQEPSSD SASAQRDLDE VKSSLVNESE NQSSSSDSEA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TCF7L1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human TCF7L1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 588 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TCF7L1

Antigène: TCF7L1 (Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1))

Autre désignation: TCF7L1

Sujet: TCF7L1 participates in the Wnt signaling pathway. It binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. It is necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis. TCF7L1 down-regulates NQO1, leading to increased mitomycin c resistance.
Alias Symbols: TCF-3, TCF3
Protein Interaction Partner: UBC, mdfic, Mdfi, DAZAP2, CTNNB1,
Protein Size: 588

Poids moléculaire: 63 kDa

ID gène: 83439

NCBI Accession: NM_031283, NP_112573

UniProt: Q9HCS4

Pathways: Signalisation WNT, Stem Cell Maintenance