TCF7L1 anticorps (Internal Region)

N° du produit ABIN6258956

Détail du produit anti-TCF7L1 anticorps

Antigène: TCF7L1 (Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TCF7L1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificité: TCF7L1 Antibody detects endogenous levels of total TCF7L1.

Homologie: Pig,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human TCF7L1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur TCF7L1

Antigène: TCF7L1 (Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1))

Autre désignation: TCF7L1 (TCF7L1 Produits)

Synonymes: anticorps TCF-3, anticorps TCF3, anticorps Tcf-3, anticorps Tcf3, anticorps bHLHb21, anticorps tcf3c, anticorps tcf3d, anticorps xtcf3, anticorps XTCF-3, anticorps tcf7l1, anticorps tcf3b, anticorps TCF-3-A, anticorps tcf-3, anticorps tcf3, anticorps tcf3a, anticorps zTcf-3, anticorps transcription factor 7 like 1, anticorps transcription factor 7 like 1 (T cell specific, HMG box), anticorps transcription factor 7 like 1 L homeolog, anticorps transcription factor 7 like 1 S homeolog, anticorps transcription factor 7 like 1b, anticorps transcription factor 7 like 1a, anticorps TCF7L1, anticorps Tcf7l1, anticorps tcf7l1.L, anticorps tcf7l1.S, anticorps tcf7l1b, anticorps tcf7l1a

Sujet:

Description: Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. Necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis (By similarity). Down-regulates NQO1, leading to increased mitomycin c resistance.

Gene: TCF7L1

Poids moléculaire: 63 kDa

ID gène: 83439

UniProt: Q9HCS4

Pathways: Signalisation WNT, Stem Cell Maintenance