HSP27 anticorps (C-Term)
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- Antigène Voir toutes HSP27 (HSPB1) Anticorps
- HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))
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Épitope
- C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp HSP27 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- SLSPEGTLTV EAPMPKLATQ SNEITIPVTF ESRAQLGGPE AAKSDETAAK
- Homologie
- Human: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against HSPB1. It was validated on Western Blot and immunohistochemistry.
- Purification
- Protein A purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human HSPB1
- Top Product
- Discover our top product HSPB1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 205 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Heat Shock Protein 27 is down-regulated in Ballooned Hepatocytes of Patients with Nonalcoholic Steatohepatitis (NASH)." dans: Scientific reports, Vol. 6, pp. 22528, (2016) (PubMed).
: "Genomic consequences of cytochrome P450 2C9 overexpression in human hepatoma cells." dans: Chemical research in toxicology, Vol. 22, Issue 5, pp. 779-87, (2009) (PubMed).
: "
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Heat Shock Protein 27 is down-regulated in Ballooned Hepatocytes of Patients with Nonalcoholic Steatohepatitis (NASH)." dans: Scientific reports, Vol. 6, pp. 22528, (2016) (PubMed).
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- Antigène
- HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))
- Autre désignation
- HSPB1 (HSPB1 Produits)
- Synonymes
- anticorps CMT2F, anticorps HMN2B, anticorps HS.76067, anticorps HSP27, anticorps HSP28, anticorps Hsp25, anticorps SRP27, anticorps 27kDa, anticorps Hsp27, anticorps cb153, anticorps cb660, anticorps hsp1, anticorps hsp25, anticorps hsp27, anticorps id:ibd2821, anticorps sb:cb660, anticorps zgc:103437, anticorps HSPB1, anticorps cmt2f, anticorps hs.76067, anticorps hsp28, anticorps heat shock protein family B (small) member 1, anticorps heat shock protein 1, anticorps heat shock protein, alpha-crystallin-related, 1, anticorps heat shock protein family B (small) member 1 L homeolog, anticorps HSPB1, anticorps Hspb1, anticorps hspb1, anticorps hspb1.L
- Sujet
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HSPB1, like the other heat shock proteins, is part of a complex system of molecular chaperones in epidermal keratinocytes.
Alias Symbols: CMT2F, DKFZp586P1322, HS.76067, HSP27, HSP28, Hsp25, HMN2B, SRP27
Protein Interaction Partner: PCSK9, HUWE1, UBC, GATA1, MAPKAPK2, AKT1, CRYAB, MAP3K7, SUMO2, HAUS1, CEP57, AARSD1, BAG3, IRS4, HSF1, LCE3A, TGFB1I1, SUMO1, NEDD8, MDM2, ASB6, ASB10, ASB17, WWOX, ASB4, ZBTB1, RPA3, RPA2, RPA1, EZH2, ESR1, SOX2, NPM1, PLG, CS, MAPKAPK3, INS, HSPB1, SGA
Protein Size: 205 - Poids moléculaire
- 23 kDa
- ID gène
- 3315
- NCBI Accession
- NM_001540, NP_001531
- UniProt
- P04792
- Pathways
- Signalisation MAPK, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of intrinsic apoptotic Signaling, VEGF Signaling
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