BAK1 anticorps (N-Term)

N° du produit ABIN2779335

Cet anticorps anti-BAK1 Polyclonal Lapin (ABIN2779335) détecte spécifiquement BAK1 dans WB. L’anticorps est réactif avec des échantillons de Humain et Cheval.

Aperçu rapide pour BAK1 anticorps (N-Term) (ABIN2779335)

Antigène: BAK1 (BCL2-Antagonist/killer 1 (BAK1))

Reactivité: Humain, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BAK1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-BAK1 anticorps

Épitope: N-Term

Fonction: BAK1 Antibody - N-terminal region

Séquence: ASGQGPGPPR QECGEPALPS ASEEQVAQDT EEVFRSYVFY RHQQEQEAEG

Homologie: Horse: 80%, Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against BAK1. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP30473-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur BAK1

Antigène: BAK1 (BCL2-Antagonist/killer 1 (BAK1))

Autre désignation: BAK1

Sujet:

Background Information: BAK1 belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

Gene Name: BCL2-antagonist/killer 1

Alternative Symbols: BAK, CDN1, BCL2L7, BAK-LIKE

Protein Name: Bcl-2 homologous antagonist/killer

Poids moléculaire: 23kDa

ID gène: 578

NCBI Accession: NP_001179

UniProt: Q16611

Pathways: Apoptose, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response