BAK1 anticorps (AA 29-187)
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- Antigène Voir toutes BAK1 Anticorps
- BAK1 (BCL2-Antagonist/killer 1 (BAK1))
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Épitope
- AA 29-187
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp BAK1 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)
- Purification
- purified
- Immunogène
- Purified recombinant fragment of human BAK1 (AA: 29-187) expressed in E. coli.
- Clone
- 2H9H7
- Isotype
- IgG2b
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- Indications d'application
- ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: 1:200 - 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- 4°C, -20°C for long term storage
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- Antigène
- BAK1 (BCL2-Antagonist/killer 1 (BAK1))
- Autre désignation
- BAK1 (BAK1 Produits)
- Synonymes
- anticorps BAK, anticorps BAK-LIKE, anticorps BCL2L7, anticorps CDN1, anticorps Bak, anticorps N-BAK1, anticorps N-Bak, anticorps Bak1, anticorps bak, anticorps bak1, anticorps BCL2 antagonist/killer 1, anticorps BCL2-antagonist/killer 1, anticorps BCL2 antagonist/killer 1 L homeolog, anticorps BAK1, anticorps Bak1, anticorps bak1.L
- Sujet
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Description: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
Aliases: BAK, CDN1, BCL2L7, BAK-LIKE
- Poids moléculaire
- 23.4 kDa
- ID gène
- 578
- HGNC
- 578
- Pathways
- Apoptose, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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