Serotonin Receptor 2B anticorps (N-Term)
Aperçu rapide pour Serotonin Receptor 2B anticorps (N-Term) (ABIN2779377)
Antigène
Voir toutes Serotonin Receptor 2B (HTR2B) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- QTESIPEEMK QIVEEQGNKL HWAALLILMV IIPTIGGNTL VILAVSLEKK
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Homologie
- Cow: 100%, Dog: 80%, Guinea Pig: 85%, Horse: 93%, Human: 100%, Pig: 87%
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Attributs du produit
- This is a rabbit polyclonal antibody against HTR2B. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human HTR2B
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 481 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Serotonin Receptor 2B (HTR2B)
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Autre désignation
- HTR2B
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Sujet
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Multiple receptor subtypes of serotonin neurotransmitters with multiple physiologic functions have been recognized. The 5-HT-2 receptors mediate many of the central and peripheral physiologic functions of serotonin. Cardiovascular effects include contraction of blood vessels and shape changes in platelets, central nervous system effects include neuronal sensitization to tactile stimuli and mediation of hallucinogenic effects of phenylisopropylamine hallucinogens.
Alias Symbols: 5-HT(2B), 5-HT2B
Protein Interaction Partner: AGTR1, SNTA1, LNX1, GNAQ, GNA11,
Protein Size: 481 -
Poids moléculaire
- 54 kDa
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ID gène
- 3357
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NCBI Accession
- NM_000867, NP_000858
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UniProt
- P41595
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Pathways
- Signalistation JAK/STAT, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Carbohydrate Metabolic Process
Antigène
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