Serotonin Receptor 2B anticorps (AA 382-481)

N° du produit ABIN6142069

Cet anticorps anti-Serotonin Receptor 2B Polyclonal Lapin (ABIN6142069) détecte spécifiquement Serotonin Receptor 2B dans WB et IF. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Serotonin Receptor 2B anticorps (AA 382-481) (ABIN6142069)

Antigène: Serotonin Receptor 2B (HTR2B)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Serotonin Receptor 2B est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-Serotonin Receptor 2B anticorps

Épitope: AA 382-481

Séquence: LFNKTFRDAF GRYITCNYRA TKSVKTLRKR SSKIYFRNPM AENSKFFKKH GIRNGINPAM YQSPMRLRSS TIQSSSIILL DTLLLTENEG DKTEEQVSYV

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 382-481 of human HTR2B (NP_000858.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:10 - 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Serotonin Receptor 2B

Antigène: Serotonin Receptor 2B (HTR2B)

Autre désignation: HTR2B

Sujet: This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. Alternatively spliced transcript variants have been found for this gene.,HTR2B,5-HT(2B),5-HT-2B,5-HT2B,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Endocrine & Metabolism,Endocrine and metabolic diseases,Obesity,Neuroscience,HTR2B

Poids moléculaire: 54 kDa

ID gène: 3357

UniProt: P41595

Pathways: Signalistation JAK/STAT, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Carbohydrate Metabolic Process