WNT2 anticorps (Middle Region)

N° du produit ABIN2779467

Détail du produit anti-WNT2 anticorps

Antigène: WNT2 (Wingless-Type MMTV Integration Site Family Member 2 (WNT2))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Mouton, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WNT2 est non-conjugé

Application: Western Blotting (WB)

Séquence: GSAKDSKGIF DWGGCSDNID YGIKFARAFV DAKERKGKDA RALMNLHNNR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 87%

Attributs du produit: This is a rabbit polyclonal antibody against WNT2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human WNT2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 360 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur WNT2

Antigène: WNT2 (Wingless-Type MMTV Integration Site Family Member 2 (WNT2))

Autre désignation: WNT2 (WNT2 Produits)

Synonymes: anticorps CG1916, anticorps D-wnt-2, anticorps DWnt-2, anticorps DWnt2, anticorps Dm DWnt2, anticorps Dm-2, anticorps Dmel\\CG1916, anticorps Dwnt-2, anticorps Wnt, anticorps Wnt-2, anticorps dWnt2, anticorps wnt2, anticorps WNT2, anticorps irp, anticorps Xwnt2, anticorps wnt-2, anticorps Xwnt-2, anticorps int1l1, anticorps 2610510E18Rik, anticorps Int1l1, anticorps Irp, anticorps Mirp, anticorps Wnt2a, anticorps INT1L1, anticorps IRP, anticorps ZfWnt2, anticorps Wnt oncogene analog 2, anticorps Wnt family member 2, anticorps wingless-type MMTV integration site family member 2, anticorps wingless-type MMTV integration site family, member 2, anticorps Wnt2, anticorps wnt2, anticorps WNT2

Sujet: WNT2 is the ligand for members of the frizzled family of seven transmembrane receptors. WNT2 is a probable developmental protein. WNT2 may be a signaling molecule which affects the development of discrete regions of tissues. WNT2 is likely to signal over only few cell diameters.The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and is expressed in the thalamus. It encodes a protein which shows 96 % amino acid identity to the mouse Wnt2 protein. Based on the map location of this gene in the 7q31 region, and the phenotype of the diminished social interaction in the knockout mouse, this gene is suggested as a strong candidate gene for autism, a prototypical pervasive development disorder. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: INT1L1, IRP
Protein Interaction Partner: RRAGC, UQCR11, HCK, AQP5, SFRP1, WNT3A, FZD1, FZD9,
Protein Size: 360

Poids moléculaire: 38 kDa

ID gène: 7472

NCBI Accession: NM_003391, NP_003382

UniProt: P09544

Pathways: Signalisation WNT