NR5A2 + LRH1 anticorps (Middle Region)

N° du produit ABIN2779697

Détail du produit anti-NR5A2 + LRH1 anticorps

Antigène: NR5A2 + LRH1 (NR5A2) (Nuclear Receptor Subfamily 5, Group A, Member 2 (NR5A2))

Épitope: Middle Region

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Cobaye, Mouton, Chien, Cheval, Poisson zèbre (Danio rerio), Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NR5A2 + LRH1 est non-conjugé

Application: Western Blotting (WB)

Séquence: LPPTDYDRSP FVTSPISMTM LHGSLQGYQT YGHFPSRAIK SEYPDPYTSS

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Sheep: 86%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against NR5A2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human NR5A2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 323 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur NR5A2 + LRH1

Antigène: NR5A2 + LRH1 (NR5A2) (Nuclear Receptor Subfamily 5, Group A, Member 2 (NR5A2))

Autre désignation: NR5A2 (NR5A2 Produits)

Synonymes: anticorps xff1rashort, anticorps NR5A2, anticorps b1f, anticorps b1f2, anticorps cpf, anticorps ff1r, anticorps ftf, anticorps ftz-f1, anticorps ftz-f1beta, anticorps hb1f, anticorps hb1f-2, anticorps lrh-1, anticorps lrh1, anticorps xff1ra, anticorps B1F, anticorps B1F2, anticorps CPF, anticorps FTF, anticorps FTZ-F1, anticorps FTZ-F1beta, anticorps LRH-1, anticorps LRH1, anticorps hB1F-2, anticorps xFF1rB, anticorps AU020803, anticorps D1Ertd308e, anticorps Ftf, anticorps UF2-H3B, anticorps Lrh-1, anticorps nuclear receptor subfamily 5 group A member 2 S homeolog, anticorps nuclear receptor subfamily 5 group A member 2, anticorps nuclear receptor subfamily 5 group A member 2 L homeolog, anticorps nuclear receptor subfamily 5, group A, member 2, anticorps nr5a2.S, anticorps NR5A2, anticorps nr5a2, anticorps nr5a2.L, anticorps Nr5a2

Sujet: NR5A2 binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. It may be responsable for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. It is a key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. It may also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.
Alias Symbols: B1F, B1F2, CPF, FTF, FTZ-F1, FTZ-F1beta, LRH-1, hB1F, hB1F-2, LRH1
Protein Interaction Partner: NSD1, NCOA1, CREB1, UBE2I, RAD54L2, NR0B2, GPS2, ILF3, PNRC2, COPS5, PNRC1, BCKDK, NRIP1, SRC, NPPA, FTH1, ALB, SUMO1, PPARGC1A, POLR2D, EDF1, SMARCD3, PROX1, Ncoa3, Ptpn6, CTNNB1,
Protein Size: 323

Poids moléculaire: 36 kDa

ID gène: 2494

NCBI Accession: NM_003822

UniProt: O60587

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway