UHRF1 anticorps (C-Term)

N° du produit ABIN2779741

Détail du produit anti-UHRF1 anticorps

Antigène: UHRF1 (Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UHRF1 est non-conjugé

Application: Western Blotting (WB)

Séquence: DDEPGPWTKE GKDRIKKLGL TMQYPEGYLE ALANREREKE NSKREEEEQQ

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against UHRF1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human UHRF1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur UHRF1

Antigène: UHRF1 (Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1))

Autre désignation: UHRF1 (UHRF1 Produits)

Synonymes: anticorps ICBP90, anticorps Np95, anticorps RNF106, anticorps hNP95, anticorps hUHRF1, anticorps AL022808, anticorps NP95, anticorps fb97f09, anticorps wu:fb97f09, anticorps zgc:63539, anticorps UHRF1, anticorps ubiquitin like with PHD and ring finger domains 1, anticorps ubiquitin-like, containing PHD and RING finger domains, 1, anticorps ubiquitin-like with PHD and ring finger domains 1, anticorps UHRF1, anticorps Uhrf1, anticorps uhrf1

Sujet: This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. Multiple transcript variants encoding different isoforms have been found for this gene.
Protein Interaction Partner: UBC, H3F3B, H3F3A, HIST2H3D, HIST2H3A, HIST2H3C, UHRF1, HIST1H3F, HIST1H3B, HIST1H3E, HIST1H3C, HIST1H3D, HIST1H3A, HIST3H3, DNMT1, PARP1, PARP2, RNF2, USP7, KAT5, MPG, BTRC, CUL1, ZPR1, RB1, PRKACA, PML, SUV39H1, EZH2, SUZ12, UHRF2, USP11, HDAC1, ELAVL1,
Protein Size: 793

Poids moléculaire: 90 kDa

ID gène: 29128

UniProt: Q96T88