AHRR anticorps (Middle Region)

N° du produit ABIN2779915

Détail du produit anti-AHRR anticorps

Antigène: AHRR (Aryl-Hydrocarbon Receptor Repressor (AHRR))

Épitope: Middle Region

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AHRR est non-conjugé

Application: Western Blotting (WB)

Séquence: CLRGGPDLLD PKGTSGDREE EDQKHILRRS PGAWGQREMH KYSYGLETPV

Homologie: Mouse: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against Ahrr. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide corresponding to a region of Mouse

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 701 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur AHRR

Antigène: AHRR (Aryl-Hydrocarbon Receptor Repressor (AHRR))

Autre désignation: Ahrr (AHRR Produits)

Synonymes: anticorps mKIAA1234, anticorps AHH, anticorps AHHR, anticorps bHLHe77, anticorps ahh, anticorps ahhr, anticorps bhlhe77, anticorps ahrr2, anticorps aryl-hydrocarbon receptor repressor, anticorps aryl hydrocarbon receptor repressor-like, anticorps uncharacterized LOC723045, anticorps aryl-hydrocarbon receptor repressor L homeolog, anticorps aryl hydrocarbon receptor repressor, anticorps aryl-hydrocarbon receptor repressor b, anticorps Ahrr, anticorps AHRR, anticorps LOC529500, anticorps LOC723045, anticorps ahrr.L, anticorps LOC100455869, anticorps ahrr, anticorps LOC100136487, anticorps ahrrb

Sujet: Ahrr mediates dioxin toxicity and is involved in regulation of cell growth and differentiation. Ahrr represses the transcription activity of AHR by competing with this transcription factor for heterodimer formation with the ARNT and subsequently binding to the xenobiotic response element (XRE) sequence present in the promoter regulatory region of variety of genes. Ahrr represses CYP1A1 by binding the XRE sequence and recruiting ANKRA2, HDAC4 and/or HDAC5. Autoregulates its expression by associating with its own XRE site.
Alias Symbols: KIAA1234, mKIAA1234
Protein Size: 701

Poids moléculaire: 78 kDa

ID gène: 11624

NCBI Accession: NM_009644, NP_033774

UniProt: Q3U1U7

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha