NKX3-1 anticorps (Middle Region)
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- Antigène Voir toutes NKX3-1 Anticorps
- NKX3-1 (NK3 Homeobox 1 (NKX3-1))
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Épitope
- Middle Region
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Reactivité
- Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NKX3-1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- TPTEPESDAH FETYLLDCEH NPGDLASAPQ VTKQPQKRSR AAFSHTQVIE
- Homologie
- Mouse: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against Nkx3-1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of Mouse Nkx3-1
- Top Product
- Discover our top product NKX3-1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 237 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- NKX3-1 (NK3 Homeobox 1 (NKX3-1))
- Autre désignation
- Nkx3-1 (NKX3-1 Produits)
- Synonymes
- anticorps Xbagpipe, anticorps Xbap, anticorps bagpipe, anticorps koza, anticorps nkx3-1, anticorps nkx3.1, anticorps si:ch211-67o1.2, anticorps nkx3a, anticorps MGC53041, anticorps MGC97890, anticorps Bax, anticorps NKX3.1, anticorps NKX3A, anticorps Nkx-3.1, anticorps BAPX2, anticorps NKX3, anticorps NK3 homeobox 1 L homeolog, anticorps NK3 homeobox 1, anticorps NK-3 transcription factor, locus 1 (Drosophila), anticorps nkx3-1.L, anticorps NKX3-1, anticorps nkx3-1, anticorps Nkx3-1
- Sujet
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Nkx3-1 is a transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. It plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Nkx3-1 acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to suppress growth and tumorigenicity of prostate carcinoma cells and plays a role in the formation of minor salivary glands (particularly palatine and lingual glands). It is essential for appropriate differentiation and secretory function of the bulbourethral gland.
Alias Symbols: Bax, NKX3.1, NKX3A, Nkx-3.1, bagpipe
Protein Interaction Partner: Fem1b, SP2,
Protein Size: 237 - Poids moléculaire
- 27 kDa
- ID gène
- 18095
- NCBI Accession
- NM_010921, NP_035051
- UniProt
- P97436
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Endopeptidase Activity, Positive Regulation of Response to DNA Damage Stimulus
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