SCN3B anticorps (N-Term)

N° du produit ABIN2780215

Détail du produit anti-SCN3B anticorps

Antigène: SCN3B (Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B))

Épitope: N-Term

Reactivité: Rat, Humain, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SCN3B est non-conjugé

Application: Western Blotting (WB)

Séquence: RPEGGKDFLI YEYRNGHQEV ESPFQGRLQW NGSKDLQDVS ITVLNVTLND

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SCN3B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SCN3B

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 215 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-SCN3B (ABIN2780215)

Ho, Zhao, Malinowski, Chahine, OLeary: "Differential expression of sodium channel ? subunits in dorsal root ganglion sensory neurons." dans: The Journal of biological chemistry, Vol. 287, Issue 18, pp. 15044-53, (2012) (PubMed).

Hu, Barajas-Martinez, Burashnikov, Springer, Wu, Varro, Pfeiffer, Koopmann, Cordeiro, Guerchicoff, Pollevick, Antzelevitch: "A mutation in the beta 3 subunit of the cardiac sodium channel associated with Brugada ECG phenotype." dans: Circulation. Cardiovascular genetics, Vol. 2, Issue 3, pp. 270-8, (2009) (PubMed).

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." dans: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

Détails sur SCN3B

Antigène: SCN3B (Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B))

Autre désignation: SCN3B (SCN3B Produits)

Synonymes: anticorps 1110001K16Rik, anticorps 4833414B02Rik, anticorps Scnb3, anticorps HSA243396, anticorps SCNB3, anticorps sodium voltage-gated channel beta subunit 3, anticorps sodium channel, voltage-gated, type III, beta, anticorps SCN3B, anticorps Scn3b

Sujet: SCN3B is one member of the sodium channel beta subunits of voltage-gated sodium channels, which are responsible for the generation and propagation of action potentials in neurons and muscle. SCN3B influences the inactivation kinetics of the sodium channel.
Alias Symbols: HSA243396, SCNB3
Protein Interaction Partner: NFASC,
Protein Size: 215

Poids moléculaire: 24 kDa

ID gène: 55800

NCBI Accession: NM_018400, NP_060870

UniProt: Q9NY72