ATF4 anticorps (N-Term)

N° du produit ABIN2780377

Cité dans 1 publication. Cet anticorps anti-ATF4 Polyclonal Lapin (ABIN2780377) détecte spécifiquement ATF4 dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye et Mouton.

Aperçu rapide pour ATF4 anticorps (N-Term) (ABIN2780377)

Antigène: ATF4 (Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATF4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-ATF4 anticorps

Épitope: N-Term

Fonction: Atf4 Antibody - N-terminal region

Séquence: VLAGDLMSPF DQSGLGAEES LGLLDDYLEV AKHLKPHGFS SDKAGSSEWP

Homologie: Cow: 86%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 92%, Rat: 100%, Sheep: 93%

Attributs du produit: This is a rabbit polyclonal antibody against Atf4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide corresponding to a region of Mouse

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP38066-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-ATF4 (ABIN2780377)

Kalinec, Thein, Parsa, Yorgason, Luxford, Urrutia, Kalinec: "Acetaminophen and NAPQI are toxic to auditory cells via oxidative and endoplasmic reticulum stress-dependent pathways." dans: Hearing research, Vol. 313, pp. 26-37, (2014) (PubMed).

Détails sur ATF4

Antigène: ATF4 (Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4))

Autre désignation: Atf4

Sujet:

Background Information: The function of Atf4 remains unknown.

Gene Name: Activating transcription factor 4

Alternative Symbols: Atf-, C/AT, CREB, Atf-4, C/ATF, CREB2, CREB-2, TAXREB, TAXREB67

Protein Name: Cyclic AMP-dependent transcription factor ATF-4

Poids moléculaire: 38kDa

ID gène: 11911

NCBI Accession: NP_033846

UniProt: Q5U4B2

Pathways: Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response