ATF4 anticorps (AA 171-270)

N° du produit ABIN559979

Détail du produit anti-ATF4 anticorps

Antigène: ATF4 (Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4))

Épitope: AA 171-270

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ATF4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Fonction: Mouse monoclonal antibody raised against a partial recombinant ATF4.

Séquence: SSTPDHSFSL ELGSEVDITE GDRKPDYTAY VAMIPQCIKE EDTPSDNDSG ICMSPESYLG SPQHSPSTRG SPNRSLPSPG VLCGSARPKP YDPPGEKMVA

Réactivité croisée: Humain, Souris

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: ATF4 (NP_001666.2, 171 a.a. ~ 270 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 2B3

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-ATF4 (ABIN559979)

Ghemrawi, Pooya, Lorentz, Gauchotte, Arnold, Gueant, Battaglia-Hsu: "Decreased vitamin B12 availability induces ER stress through impaired SIRT1-deacetylation of HSF1." dans: Cell death & disease, Vol. 4, pp. e553, (2013) (PubMed).

Wang, Wang, Zhang, Qu, Liu: "A protective role of heme-regulated eIF2? kinase in cadmium-induced toxicity in erythroid cells." dans: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 62, pp. 880-91, (2013) (PubMed).

Cole, Kuhn, Green-Mitchell, Leone, Raab, Nadler, Chakrabarti: "12/15-Lipoxygenase signaling in the endoplasmic reticulum stress response." dans: American journal of physiology. Endocrinology and metabolism, Vol. 302, Issue 6, pp. E654-65, (2012) (PubMed).

Suragani, Zachariah, Velazquez, Liu, Sun, Townes, Chen: "Heme-regulated eIF2? kinase activated Atf4 signaling pathway in oxidative stress and erythropoiesis." dans: Blood, Vol. 119, Issue 22, pp. 5276-84, (2012) (PubMed).

Meister, Frey, Lang, Gaipl, Schett, Schlötzer-Schrehardt, Voll: "Calcium channel blocker verapamil enhances endoplasmic reticulum stress and cell death induced by proteasome inhibition in myeloma cells." dans: Neoplasia (New York, N.Y.), Vol. 12, Issue 7, pp. 550-61, (2010) (PubMed).

Détails sur ATF4

Antigène: ATF4 (Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4))

Autre désignation: ATF4 (ATF4 Produits)

Synonymes: anticorps CREB-2, anticorps CREB2, anticorps TAXREB67, anticorps TXREB, anticorps ATF4, anticorps atf-4, anticorps creb-2, anticorps creb2, anticorps taxreb67, anticorps txreb, anticorps atf4, anticorps wu:fj01c08, anticorps wu:fk30b04, anticorps zgc:85951, anticorps sb:eu681, anticorps wu:fb08f07, anticorps zgc:171702, anticorps Atf-4, anticorps C/ATF, anticorps ATF4-I, anticorps atf4-a, anticorps atf4-b, anticorps atf4-ii, anticorps activating transcription factor 4, anticorps activating transcription factor 4 L homeolog, anticorps activating transcription factor 4a, anticorps activating transcription factor 4b, anticorps activating transcription factor 4 S homeolog, anticorps ATF4, anticorps atf4, anticorps Atf4, anticorps atf4.L, anticorps atf4a, anticorps atf4b, anticorps atf4.S

Sujet: Full Gene Name: activating transcription factor 4 (tax-responsive enhancer element B67)
Synonyms: CREB-2,CREB2,TAXREB67,TXREB

ID gène: 468

NCBI Accession: NM_001675

Pathways: Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response