NR1H2 anticorps (N-Term)

N° du produit ABIN2780830

Détail du produit anti-NR1H2 anticorps

Antigène: NR1H2 (Nuclear Receptor Subfamily 1, Group H, Member 2 (NR1H2))

Épitope: N-Term

Reactivité: Humain, Rat, Chien, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NR1H2 est non-conjugé

Application: Western Blotting (WB)

Séquence: GNGPPQPGAP SSSPTVKEEG PEPWPGGPDP DVPGTDEASS ACSTDWVIPD

Homologie: Dog: 90%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against NR1H2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human NR1H2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 460 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-NR1H2 (ABIN2780830)

Bogan, Hennebold: "The reverse cholesterol transport system as a potential mediator of luteolysis in the primate corpus luteum." dans: Reproduction (Cambridge, England), Vol. 139, Issue 1, pp. 163-76, (2009) (PubMed).

Détails sur NR1H2

Antigène: NR1H2 (Nuclear Receptor Subfamily 1, Group H, Member 2 (NR1H2))

Autre désignation: NR1H2 (NR1H2 Produits)

Synonymes: anticorps NR1H2, anticorps lxr-b, anticorps lxrb, anticorps ner, anticorps ner-i, anticorps rip15, anticorps unr, anticorps DKFZp468A0622, anticorps AI194859, anticorps LXR, anticorps LXRB, anticorps LXRbeta, anticorps NER1, anticorps OR-1, anticorps RIP15, anticorps UR, anticorps Unr, anticorps Unr2, anticorps LXR-b, anticorps NER, anticorps NER-I, anticorps UNR, anticorps nuclear receptor subfamily 1 group H member 2, anticorps nuclear receptor subfamily 1, group H, member 2, anticorps nuclear receptor subfamily 1 group H member 2 L homeolog, anticorps NR1H2, anticorps nr1h2, anticorps Nr1h2, anticorps nr1h2.L

Sujet: The LX receptors (LXRs) were originally identified as orphan members of the nuclear receptor superfamily because their ligands were unknown. Like other receptors in the family, LXRs heterodimerize with retinoid X receptor and bind to specific response elements (LXREs) characterized by direct repeats separated by 4 nucleotides. Two genes, alpha (LXRA) and beta, are known to encode LXR proteins.The LX receptors (LXRs) were originally identified as orphan members of the nuclear receptor superfamily because their ligands were unknown. Like other receptors in the family, LXRs heterodimerize with retinoid X receptor (see MIM 180245) and bind to specific response elements (LXREs) characterized by direct repeats separated by 4 nucleotides. Two genes, alpha (LXRA, MIM 602423) and beta, are known to encode LXR proteins (Song et al., 1995).[supplied by OMIM].
Alias Symbols: LXR-b, LXRB, NER, NER-I, RIP15, UNR
Protein Interaction Partner: RXRG, MDFI, KDM1A, SUV39H1, ACVRL1, LAMC3, NCOR2, YY1, NPY, CDKN1A, PPARGC1B, PDCD4, PIAS1, USP7, PRKCA, SENP3, CORO2A, MPP1, COL4A5, CHD3, RMI1, CSAD, DUSP12, C14orf1, FAF1, SPRY2, HMGXB4, SORBS2, BAG6, VIM, UBE2D1, SMPD1, ROBO2, NCOR1, NRIP1, NCOA3, VDR
Protein Size: 460

Poids moléculaire: 51 kDa

ID gène: 7376

NCBI Accession: NM_007121, NP_009052

UniProt: Q68CY8

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding