ABCC1 anticorps (Middle Region)

N° du produit ABIN2781507

Détail du produit anti-ABCC1 anticorps

Antigène: ABCC1 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1))

Épitope: Middle Region

Reactivité: Humain, Rat, Boeuf (Vache), Chien, Lapin, Cobaye, Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ABCC1 est non-conjugé

Application: Western Blotting (WB)

Séquence: LFISFLSIFL FMCNHVSALA SNYWLSLWTD DPIVNGTQEH TKVRLSVYGA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 77%, Horse: 92%, Human: 100%, Pig: 100%, Rabbit: 93%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against ABCC1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human ABCC1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1531 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ABCC1

Antigène: ABCC1 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1))

Autre désignation: ABCC1 (ABCC1 Produits)

Synonymes: anticorps ABC29, anticorps ABCC, anticorps GS-X, anticorps MRP, anticorps MRP1, anticorps Abcc1a, anticorps Abcc1b, anticorps Mdrap, anticorps Mrp1, anticorps Avcc1a, anticorps Mrp, anticorps ABCC13, anticorps ATP binding cassette subfamily C member 1, anticorps ATP-binding cassette, sub-family C (CFTR/MRP), member 1, anticorps multidrug resistance-associated protein 1, anticorps ABCC1, anticorps Abcc1, anticorps LOC100152428, anticorps LOC100346553

Sujet: ABCC1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternative splicing by exon deletion results in several splice variants but maintains the original open reading frame in all forms. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternative splicing by exon deletion results in several splice variants but maintains the original open reading frame in all forms.
Alias Symbols: ABC29, ABCC, DKFZp686N04233, DKFZp781G125, GS-X, MRP, MRP1
Protein Interaction Partner: UBC, ABCC1, CAV1, TRAF3, NPM1, AZGP1, STT3B, RAVER1, MCU, MRPL17, TMCO1, ATP6V1H, TMX2, TMOD2, NDUFAF3, FKBP8, PUF60, PGRMC2, FLOT1, PDCD6IP, ATP6V1F, EIF3C, PDHX, VDAC3, SURF1, STX4, SAFB, RPS7, NDUFB9, DBT, TMEM173, UNC93B1,
Protein Size: 1531

Poids moléculaire: 171 kDa

ID gène: 4363

NCBI Accession: NM_004996, NP_004987

UniProt: P33527

Pathways: SARS-CoV-2 Protein Interactome