CYBB anticorps (C-Term)

N° du produit ABIN2781794

Détail du produit anti-CYBB anticorps

Antigène: CYBB (Cytochrome B-245, beta Polypeptide (CYBB))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYBB est non-conjugé

Application: Western Blotting (WB)

Séquence: YGRPNWDNEF KTIASQHPNT RIGVFLCGPE ALAETLSKQS ISNSESGPRG

Homologie: Cow: 79%, Dog: 93%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CYBB. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human CY24B

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 570 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CYBB

Antigène: CYBB (Cytochrome B-245, beta Polypeptide (CYBB))

Autre désignation: CYBB (CYBB Produits)

Synonymes: anticorps zgc:64144, anticorps cgd, anticorps gp91-1, anticorps gp91-phox, anticorps gp91phox, anticorps nox2, anticorps NOX2, anticorps cybb, anticorps NOX1, anticorps AMCBX2, anticorps CGD, anticorps GP91-1, anticorps GP91-PHOX, anticorps GP91PHOX, anticorps p91-PHOX, anticorps Nox2, anticorps C88302, anticorps CGD91-phox, anticorps Cgd, anticorps Cyd, anticorps Gp91-phox, anticorps CYBB, anticorps cytochrome b-245, beta polypeptide (chronic granulomatous disease), anticorps cytochrome b-245, beta polypeptide, anticorps cytochrome b-245 heavy chain, anticorps cytochrome b-245, beta polypeptide L homeolog, anticorps cytochrome b-245 beta polypeptide, anticorps cytochrome b-245 beta chain, anticorps NADPH oxidase heavy chain subunit, anticorps cybb, anticorps CYBB, anticorps cybb.L, anticorps Cybb, anticorps GP91-PHOX

Sujet: Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase, neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.
Alias Symbols: CGD, NOX2, IMD34, AMCBX2, GP91-1, GP91PHOX, p91-PHOX, GP91-PHOX,
Protein Interaction Partner: IQGAP1, ACTB, UBC, SUMO1, RAC1, NCF4, NCF2, NCF1, CYBA, ACTG1,
Protein Size: 570

Poids moléculaire: 62 kDa

ID gène: 1536

NCBI Accession: NM_000397, NP_000388

UniProt: P04839