LFNG anticorps (N-Term)

N° du produit ABIN2782070

Cet anticorps anti-LFNG Polyclonal Lapin (ABIN2782070) détecte spécifiquement LFNG dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Cobaye, Boeuf (Vache), Cheval et Saccharomyces cerevisiae.

Aperçu rapide pour LFNG anticorps (N-Term) (ABIN2782070)

Antigène: LFNG (LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG))

Reactivité: Humain, Souris, Rat, Cobaye, Boeuf (Vache), Cheval, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LFNG est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-LFNG anticorps

Épitope: N-Term

Fonction: LFNG Antibody - N-terminal region

Séquence: LSEYFSLLTR ARRDAGPPPG AAPRPADGHP RPLAEPLAPR DVFIAVKTTK

Homologie: Cow: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Yeast: 100%

Attributs du produit: This is a rabbit polyclonal antibody against LFNG. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human LFNG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP44923-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur LFNG

Antigène: LFNG (LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG))

Autre désignation: LFNG

Sujet:

Background Information: This gene is a member of the glycosyltransferase 31 gene family. Members of this gene family, which also includes the MFNG (GeneID: 4242) and RFNG (GeneID: 5986) genes, encode evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, these proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. The protein encoded by this gene is predicted to be a single-pass type II Golgi membrane protein but it may also be secreted and proteolytically processed like the related proteins in mouse and Drosophila (PMID: 9187150). Mutations in this gene have been associated with autosomal recessive spondylocostal dysostosis 3.

Gene Name: LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

Alternative Symbols: SCDO3

Protein Name: beta-1,3-N-acetylglucosaminyltransferase lunatic fringe

Poids moléculaire: 39kDa

ID gène: 3955

NCBI Accession: NP_001035258

UniProt: Q8NES3

Pathways: Signalisation Notch