ZP2 anticorps (C-Term)
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- Antigène Voir toutes ZP2 Anticorps
- ZP2 (Zona Pellucida Glycoprotein 2 (ZP2))
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Épitope
- C-Term
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Reactivité
- Humain, Rat, Cheval, Cobaye, Lapin, Boeuf (Vache), Chien
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ZP2 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- PDSFPQWNVV VDGCAYDLDN YQTTFHPVGS SVTHPDHYQR FDMKAFAFVS
- Homologie
- Cow: 79%, Dog: 86%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Rabbit: 93%, Rat: 86%
- Attributs du produit
- This is a rabbit polyclonal antibody against ZP2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human ZP2
- Top Product
- Discover our top product ZP2 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 745 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- ZP2 (Zona Pellucida Glycoprotein 2 (ZP2))
- Autre désignation
- ZP2 (ZP2 Produits)
- Synonymes
- anticorps fa12e07, anticorps wu:fa12e07, anticorps zgc:152728, anticorps zp2, anticorps Zp-2, anticorps ZPA, anticorps zona pellucida glycoprotein 2, tandem duplicate 5, anticorps zona pellucida glycoprotein 2, anticorps zp2.5, anticorps Zp2, anticorps ZP2
- Sujet
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The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. ZP2 is a structural component of the zona pellucida and functions in secondary binding and penetration of acrosome-reacted spermatozoa. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies.The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene is a structural component of the zona pellucida and functions in secondary binding and penetration of acrosome-reacted spermatozoa. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies.
Alias Symbols: ZPA, Zp-2
Protein Interaction Partner: ZPBP, ACR,
Protein Size: 745 - Poids moléculaire
- 68 kDa
- ID gène
- 7783
- NCBI Accession
- NM_003460, NP_003451
- UniProt
- Q05996
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