CDT1 anticorps (C-Term)

N° du produit ABIN2782592

Détail du produit anti-CDT1 anticorps

Antigène: CDT1 (Chromatin Licensing and DNA Replication Factor 1 (CDT1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Porc, Boeuf (Vache), Chien, Lapin, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDT1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: PATPPATPPA ASPSALKGVS QDLLERIRAK EAQKQLAQMT RCPEQEQRLQ

Homologie: Cow: 93%, Dog: 77%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Yeast: 85%

Attributs du produit: This is a rabbit polyclonal antibody against CDT1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human CDT1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 546 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CDT1

Antigène: CDT1 (Chromatin Licensing and DNA Replication Factor 1 (CDT1))

Autre désignation: CDT1 (CDT1 Produits)

Synonymes: anticorps CDT1, anticorps fc37h07, anticorps im:7158083, anticorps wu:fc37h07, anticorps wu:fi38h09, anticorps xcdt1, anticorps DUP, anticorps RIS2, anticorps 2610318F11Rik, anticorps AW545653, anticorps C76791, anticorps Ris2, anticorps dup, anticorps ris2, anticorps chromatin licensing and DNA replication factor 1, anticorps chromatin licensing and DNA replication factor 1 L homeolog, anticorps CDT1, anticorps cdt1, anticorps Cdt1, anticorps cdt1.L

Sujet: CDT1 cooperates with CDC6 to promote the loading of the mini-chromosome maintenance complex onto chromatin to form the pre-replication complex necessary to initiate DNA replication. It binds DNA in a sequence-, strand-, and conformation-independent manner and is a potential oncogene.
Alias Symbols: DUP, RIS2
Protein Interaction Partner: FBXO31, SKP1, RBX1, CUL1, DTL, PCNA, HECW2, CDK2, CDC6, CDC5L, ORC2, ORC1, GMNN, DGCR8, UBC, SKP2, CDK1, CCNB1, CCNA2, FOXO3, DDB1, COPS5, CUL4A, CUL4B, SMARCA5, MCM6, MAPK8, MAPK1, HDAC11, KAT7, CCNA1, DDB2, CDK4, CCNE1, TP63, TP73, EP300, KAT2B, CDT1, U
Protein Size: 546

Poids moléculaire: 60 kDa

ID gène: 81620

NCBI Accession: NM_030928, NP_112190

UniProt: Q9H211

Pathways: Signalisation MAPK, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA