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Arrestin 3 anticorps (Middle Region)

ARRB2 Reactivité: Humain, Souris, Rat, Porc, Chien, Boeuf (Vache), Cheval, Lapin, Poisson zèbre (Danio rerio), Cobaye WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2783190
  • Antigène Voir toutes Arrestin 3 (ARRB2) Anticorps
    Arrestin 3 (ARRB2) (Arrestin, beta 2 (ARRB2))
    Épitope
    • 15
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    Humain, Souris, Rat, Porc, Chien, Boeuf (Vache), Cheval, Lapin, Poisson zèbre (Danio rerio), Cobaye
    Hôte
    • 39
    • 5
    • 3
    Lapin
    Clonalité
    • 42
    • 5
    Polyclonal
    Conjugué
    • 28
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Arrestin 3 est non-conjugé
    Application
    • 39
    • 17
    • 16
    • 13
    • 13
    • 12
    • 12
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    RLVIRKVQFA PEKPGPQPSA ETTRHFLMSD RSLHLEASLD KELYYHGEPL
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
    Attributs du produit
    This is a rabbit polyclonal antibody against ARRB2. It was validated on Western Blot and immunohistochemistry.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human ARRB2
    Top Product
    Discover our top product ARRB2 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 409 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    Arrestin 3 (ARRB2) (Arrestin, beta 2 (ARRB2))
    Autre désignation
    ARRB2 (ARRB2 Produits)
    Synonymes
    anticorps ARRB2, anticorps arb2, anticorps arr2, anticorps arrestin, anticorps barr2, anticorps betaarr2, anticorps ARB2, anticorps ARR2, anticorps BARR2, anticorps BARRES, anticorps AI326910, anticorps AW122872, anticorps arrb2, anticorps zgc:64007, anticorps arrestin beta 2, anticorps arrestin, beta 2, anticorps arrestin beta 2 L homeolog, anticorps arrestin, beta 2b, anticorps ARRB2, anticorps arrb2, anticorps Arrb2, anticorps arrb2.L, anticorps arrb2b
    Sujet
    Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. ARRB2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors.Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.
    Alias Symbols: ARB2, ARR2, DKFZp686L0365, BARR2
    Protein Interaction Partner: UBC, SRC, MAPK9, INSR, AKT1, USP33, ADRB2, TBXA2R, CYTH1, PTGDS, BAI1, LIMK1, CFL1, CSK, AGTR1, MAP2K4, MAPK10, MAP3K5, GCG, NFKBIA, MDM2, IGF1R, CLTC, ADRB1, HIPK3, EDNRA, gag-pol, ARRDC3, ARRDC4, SIRT1, PDE4D, Mlnr, Trhr, C5AR1, SLC9A5, AP2M1, HCRTR1, F
    Protein Size: 409
    Poids moléculaire
    46 kDa
    ID gène
    409
    NCBI Accession
    NM_199004, NP_945355
    UniProt
    P32121
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Phototransduction, Thromboxane A2 Receptor Signaling
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