SPRY4 anticorps (Middle Region)

N° du produit ABIN2784290

Détail du produit anti-SPRY4 anticorps

Antigène: SPRY4 (Sprouty RTK Signaling Antagonist 4 (SPRY4))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPRY4 est non-conjugé

Application: Western Blotting (WB)

Séquence: LCYLPATGCV KLAQRGYDRL RRPGCRCKHT NSVICKAASG DAKTSRPDKP

Homologie: Cow: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against SPRY4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SPRY4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 322 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SPRY4

Antigène: SPRY4 (Sprouty RTK Signaling Antagonist 4 (SPRY4))

Autre désignation: SPRY4 (SPRY4 Produits)

Synonymes: anticorps SPRY4, anticorps LOC100218545, anticorps HH17, anticorps A030006O18Rik, anticorps sprouty4, anticorps sprouty RTK signaling antagonist 4, anticorps sprouty (Drosophila) homolog 4, anticorps sprouty homolog 4 (Drosophila), anticorps Spry4, anticorps SPRY4, anticorps spry4

Sujet: SPRY4 is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. It is positioned upstream of RAS (see HRAS, MIM 190020) activation and impairs the formation of active GTP-RAS (Leeksma et al., 2002 [PubMed 12027893]).
Alias Symbols: -
Protein Interaction Partner: GRB2, SPRY2, SPRY4, TESK1, RAF1, CBL,
Protein Size: 322

Poids moléculaire: 35 kDa

ID gène: 81848

NCBI Accession: NM_030964, NP_112226

UniProt: Q9C004