ASZ1 anticorps (Middle Region)

N° du produit ABIN2784974

Détail du produit anti-ASZ1 anticorps

Antigène: ASZ1 (Ankyrin Repeat, SAM and Basic Leucine Zipper Domain Containing 1 (ASZ1))

Épitope: Middle Region

Reactivité: Humain, Rat, Souris, Cobaye, Cheval, Lapin, Boeuf (Vache), Chien, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ASZ1 est non-conjugé

Application: Western Blotting (WB)

Séquence: GKMPSEIAKR NKHHEIFNLL SFTLNPLEGK LQQLTKEDTI CKILTTDSDR

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%

Attributs du produit: This is a rabbit polyclonal antibody against ASZ1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human ASZ1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 475 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ASZ1

Antigène: ASZ1 (Ankyrin Repeat, SAM and Basic Leucine Zipper Domain Containing 1 (ASZ1))

Autre désignation: ASZ1 (ASZ1 Produits)

Synonymes: anticorps Gasz, anticorps GASZ, anticorps gasz, anticorps MGC56332, anticorps zgc:56332, anticorps ALP1, anticorps ANKL1, anticorps C7orf7, anticorps CT1.19, anticorps Orf3, anticorps 4933400N19Rik, anticorps ORF3, anticorps ankyrin repeat, SAM and basic leucine zipper domain containing 1, anticorps Asz1, anticorps ASZ1, anticorps asz1

Sujet: ASZ1 plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity.ASZ1 acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process.ASZ1 is required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in regulation of retrotransposons.ASZ1 may act by mediating protein-protein interactions during germ cell maturation.
Alias Symbols: ALP1, ANKL1, C7orf7, GASZ, MGC26634, Orf3, CT1.19
Protein Interaction Partner: TSG101,
Protein Size: 475

Poids moléculaire: 53 kDa

ID gène: 136991

NCBI Accession: NM_130768, NP_570124

UniProt: Q8WWH4