Actl7b anticorps (Middle Region)
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- Antigène Voir toutes Actl7b Anticorps
- Actl7b (Actin-Like 7b (Actl7b))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Actl7b est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- KLITIGQERF RCSEMLFQPS LAGSTQPGLP ELTAACLGRC QDTGFKEEMA
- Homologie
- Cow: 77%, Dog: 83%, Human: 100%, Mouse: 85%, Rat: 92%
- Attributs du produit
- This is a rabbit polyclonal antibody against ACTL7B. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human ACTL7B
- Top Product
- Discover our top product Actl7b Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 416 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- Actl7b (Actin-Like 7b (Actl7b))
- Autre désignation
- ACTL7B (Actl7b Produits)
- Synonymes
- anticorps ACTL7B, anticorps Tact1, anticorps actin-like 7b, anticorps actin like 7B, anticorps Actl7b, anticorps ACTL7B
- Sujet
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ACTL7B is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. Based on mutational analysis of the ACTL7B gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. Unlike ACTL7A, the ACTL7B gene is expressed predominantly in the testis, however, its exact function is not known.The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7B), and related gene, ACTL7A, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7B gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. Unlike ACTL7A, the ACTL7B gene is expressed predominantly in the testis, however, its exact function is not known.
Alias Symbols: Tact1
Protein Interaction Partner: APP,
Protein Size: 416 - Poids moléculaire
- 46 kDa
- ID gène
- 10880
- NCBI Accession
- NM_006686, NP_006677
- UniProt
- Q9Y614
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